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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Mass Cytometry for the Assessment of Immune Reconstitution After Hematopoietic Stem Cell Transplantation
|
|---|---|
| Published in |
Frontiers in immunology, July 2018
|
| DOI | 10.3389/fimmu.2018.01672 |
| Pubmed ID | |
| Authors |
Lauren Stern, Helen McGuire, Selmir Avdic, Simone Rizzetto, Barbara Fazekas de St Groth, Fabio Luciani, Barry Slobedman, Emily Blyth |
| Abstract |
Mass cytometry, or Cytometry by Time-Of-Flight, is a powerful new platform for high-dimensional single-cell analysis of the immune system. It enables the simultaneous measurement of over 40 markers on individual cells through the use of monoclonal antibodies conjugated to rare-earth heavy-metal isotopes. In contrast to the fluorochromes used in conventional flow cytometry, metal isotopes display minimal signal overlap when resolved by single-cell mass spectrometry. This review focuses on the potential of mass cytometry as a novel technology for studying immune reconstitution in allogeneic hematopoietic stem cell transplant (HSCT) recipients. Reconstitution of a healthy donor-derived immune system after HSCT involves the coordinated regeneration of innate and adaptive immune cell subsets in the recipient. Mass cytometry presents an opportunity to investigate immune reconstitution post-HSCT from a systems-level perspective, by allowing the phenotypic and functional features of multiple cell populations to be assessed simultaneously. This review explores the current knowledge of immune reconstitution in HSCT recipients and highlights recent mass cytometry studies contributing to the field. |
X Demographics
The data shown below were collected from the profiles of 37 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 14% |
| Australia | 4 | 11% |
| United Kingdom | 2 | 5% |
| Argentina | 2 | 5% |
| Mexico | 2 | 5% |
| Chile | 1 | 3% |
| South Africa | 1 | 3% |
| Sweden | 1 | 3% |
| Russia | 1 | 3% |
| Other | 3 | 8% |
| Unknown | 15 | 41% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 22 | 59% |
| Scientists | 10 | 27% |
| Practitioners (doctors, other healthcare professionals) | 4 | 11% |
| Science communicators (journalists, bloggers, editors) | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 136 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 136 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 23 | 17% |
| Student > Ph. D. Student | 21 | 15% |
| Other | 17 | 13% |
| Student > Master | 15 | 11% |
| Student > Doctoral Student | 8 | 6% |
| Other | 19 | 14% |
| Unknown | 33 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 29 | 21% |
| Immunology and Microbiology | 22 | 16% |
| Biochemistry, Genetics and Molecular Biology | 21 | 15% |
| Agricultural and Biological Sciences | 11 | 8% |
| Computer Science | 4 | 3% |
| Other | 13 | 10% |
| Unknown | 36 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 23. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 August 2021.
All research outputs
#1,640,480
of 25,385,509 outputs
Outputs from Frontiers in immunology
#1,475
of 31,537 outputs
Outputs of similar age
#33,626
of 341,301 outputs
Outputs of similar age from Frontiers in immunology
#46
of 643 outputs
Altmetric has tracked 25,385,509 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 31,537 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 341,301 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 643 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.