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Mendeley readers
Attention Score in Context
| Title |
The Coagulation Factors Fibrinogen, Thrombin, and Factor XII in Inflammatory Disorders—A Systematic Review
|
|---|---|
| Published in |
Frontiers in immunology, July 2018
|
| DOI | 10.3389/fimmu.2018.01731 |
| Pubmed ID | |
| Authors |
Kerstin Göbel, Susann Eichler, Heinz Wiendl, Triantafyllos Chavakis, Christoph Kleinschnitz, Sven G. Meuth |
| Abstract |
The interaction of coagulation factors has been shown to go beyond their traditional roles in hemostasis and to affect the development of inflammatory diseases. Key molecular players, such as fibrinogen, thrombin, or factor XII have been mechanistically and epidemiologically linked to inflammatory disorders like multiple sclerosis (MS), rheumatoid arthritis (RA), and colitis. To systematically review the evidence for a role of coagulation factors, especially factor XII, fibrinogen, and thrombin in inflammatory disorders like MS, RA, and bowel disorders. A systematic literature search was done in the PubMed database to identify studies about coagulation factors in inflammatory diseases. Original articles and reviews investigating the role of the kallikrein-kinin and the coagulation system in mouse and humans were included. We identified 43 animal studies dealing with inflammatory disorders and factors of the kallikrein-kinin or the coagulation system. Different immunological influences are described and novel molecular mechanisms linking coagulation and inflammation are reported. A number of studies have highlighted coagulation factors to tip the balance between hemostasis and thrombosis and between protection from infection and extensive inflammation. To optimize the treatment of chronic inflammatory disorders by these factors, further studies are necessary. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 40% |
| Colombia | 1 | 20% |
| Switzerland | 1 | 20% |
| Unknown | 1 | 20% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 220 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 220 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 25 | 11% |
| Researcher | 24 | 11% |
| Student > Bachelor | 24 | 11% |
| Student > Master | 13 | 6% |
| Other | 12 | 5% |
| Other | 33 | 15% |
| Unknown | 89 | 40% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 30 | 14% |
| Biochemistry, Genetics and Molecular Biology | 27 | 12% |
| Immunology and Microbiology | 11 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 10 | 5% |
| Agricultural and Biological Sciences | 9 | 4% |
| Other | 32 | 15% |
| Unknown | 101 | 46% |
Attention Score in Context
This research output has an Altmetric Attention Score of 17. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 August 2022.
All research outputs
#2,170,347
of 25,385,509 outputs
Outputs from Frontiers in immunology
#2,097
of 31,537 outputs
Outputs of similar age
#43,357
of 341,301 outputs
Outputs of similar age from Frontiers in immunology
#65
of 643 outputs
Altmetric has tracked 25,385,509 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 31,537 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 341,301 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 643 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 89% of its contemporaries.