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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Follicular Helper T Cells in Systemic Lupus Erythematosus
|
|---|---|
| Published in |
Frontiers in immunology, August 2018
|
| DOI | 10.3389/fimmu.2018.01793 |
| Pubmed ID | |
| Authors |
Sun Jung Kim, Kyungwoo Lee, Betty Diamond |
| Abstract |
CD4+ follicular helper T (Tfh) cells constitute a subset of effector T cells that participate in the generation of high-affinity humoral responses. They express the chemokine receptor CXCR5 and produce the cytokine IL-21, both of which are required for their contribution to germinal center formation. Uncontrolled expansion of Tfh cells is observed in various mouse models of systemic autoimmune diseases and in patients with these diseases. In particular, the frequency of circulating Tfh is correlated with disease activity and anti-DNA antibody titer in patients with systemic lupus erythematosus. Recent studies reveal functional diversity within the Tfh population in both humans and mice. We will summarize here the molecular mechanisms for Tfh cell generation, survival and function in both humans and mice, and the relationship between Tfh cells and autoimmune disease in animal models and in patients. |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Venezuela, Bolivarian Republic of | 4 | 57% |
| Unknown | 3 | 43% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 7 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 108 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 108 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 14 | 13% |
| Researcher | 12 | 11% |
| Student > Postgraduate | 11 | 10% |
| Student > Ph. D. Student | 11 | 10% |
| Student > Bachelor | 8 | 7% |
| Other | 15 | 14% |
| Unknown | 37 | 34% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 22 | 20% |
| Immunology and Microbiology | 22 | 20% |
| Biochemistry, Genetics and Molecular Biology | 15 | 14% |
| Agricultural and Biological Sciences | 5 | 5% |
| Chemistry | 2 | 2% |
| Other | 4 | 4% |
| Unknown | 38 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 September 2019.
All research outputs
#7,782,070
of 25,385,509 outputs
Outputs from Frontiers in immunology
#9,048
of 31,537 outputs
Outputs of similar age
#123,383
of 341,622 outputs
Outputs of similar age from Frontiers in immunology
#223
of 616 outputs
Altmetric has tracked 25,385,509 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 31,537 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.4. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 341,622 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.
We're also able to compare this research output to 616 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.