Title |
A Review of the Nonpressor and Nonantidiuretic Actions of the Hormone Vasopressin
|
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Published in |
Frontiers in Medicine, March 2015
|
DOI | 10.3389/fmed.2015.00019 |
Pubmed ID | |
Authors |
Gaurang P. Mavani, Maria V. DeVita, Michael F. Michelis |
Abstract |
The pressor and antidiuretic actions of arginine vasopressin (AVP) have been well documented. This review focuses on the less widely appreciated actions of AVP which also have important physiologic functions and when better understood may provide important insights into common disease states. These actions include effects on pain perception and bone structure as well as important relationships to the varied components of metabolic syndrome. These include effects on blood glucose, lipid levels, and blood pressure. AVP may also play a role in the progression of chronic kidney disease and effect physiologic changes relating to aging, abnormal social behavior, and cognitive function. Important cellular responses including cell proliferation, inflammation, and control of infection and their relationship to AVP are described. Finally, the effects of AVP on hemostasis and the hypothalamic-pituitary-adrenal axis are noted. The goal of this summary of the various actions of AVP is to direct attention to the potential benefits of research in these underemphasized areas of importance. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 14% |
Unknown | 6 | 86% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 4 | 57% |
Scientists | 2 | 29% |
Practitioners (doctors, other healthcare professionals) | 1 | 14% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Mexico | 1 | 1% |
United States | 1 | 1% |
Unknown | 87 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 18 | 20% |
Student > Bachelor | 16 | 18% |
Researcher | 8 | 9% |
Student > Doctoral Student | 7 | 8% |
Student > Master | 7 | 8% |
Other | 13 | 15% |
Unknown | 20 | 22% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 23 | 26% |
Agricultural and Biological Sciences | 12 | 13% |
Biochemistry, Genetics and Molecular Biology | 9 | 10% |
Neuroscience | 6 | 7% |
Psychology | 3 | 3% |
Other | 11 | 12% |
Unknown | 25 | 28% |