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Small Molecule Radiopharmaceuticals – A Review of Current Approaches

Overview of attention for article published in Frontiers in Medicine, February 2016
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Title
Small Molecule Radiopharmaceuticals – A Review of Current Approaches
Published in
Frontiers in Medicine, February 2016
DOI 10.3389/fmed.2016.00005
Pubmed ID
Authors

Shubhra Chaturvedi, Anil K. Mishra

Abstract

Radiopharmaceuticals are an integral component of nuclear medicine and are widely applied in diagnostics and therapy. Though widely applied, the development of an "ideal" radiopharmaceutical can be challenging. Issues such as specificity, selectivity, sensitivity, and feasible chemistry challenge the design and synthesis of radiopharmaceuticals. Over time, strategies to address the issues have evolved by making use of new technological advances in the fields of biology and chemistry. This review presents the application of few advances in design and synthesis of radiopharmaceuticals. The topics covered are bivalent ligand approach and lipidization as part of design modifications for enhanced selectivity and sensitivity and novel synthetic strategies for optimized chemistry and radiolabeling of radiopharmaceuticals.

X Demographics

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 64 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 25%
Student > Bachelor 10 15%
Student > Master 7 11%
Researcher 6 9%
Other 4 6%
Other 7 11%
Unknown 15 23%
Readers by discipline Count As %
Chemistry 24 37%
Pharmacology, Toxicology and Pharmaceutical Science 8 12%
Biochemistry, Genetics and Molecular Biology 4 6%
Neuroscience 3 5%
Physics and Astronomy 3 5%
Other 7 11%
Unknown 16 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 July 2016.
All research outputs
#18,465,704
of 22,880,230 outputs
Outputs from Frontiers in Medicine
#3,938
of 5,694 outputs
Outputs of similar age
#216,979
of 298,778 outputs
Outputs of similar age from Frontiers in Medicine
#5
of 8 outputs
Altmetric has tracked 22,880,230 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,694 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.0. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 298,778 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.