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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Oral Vitamin B12 Replacement for the Treatment of Pernicious Anemia
|
|---|---|
| Published in |
Frontiers in Medicine, August 2016
|
| DOI | 10.3389/fmed.2016.00038 |
| Pubmed ID | |
| Authors |
Catherine Qiu Hua Chan, Lian Leng Low, Kheng Hock Lee |
| Abstract |
Many patients with pernicious anemia are treated with lifelong intramuscular (IM) vitamin B12 replacement. As early as the 1950s, there were studies suggesting that oral vitamin B12 replacement may provide adequate absorption. Nevertheless, oral vitamin B12 replacement in patients with pernicious anemia remains uncommon in clinical practice. The objective of this review is to provide an update on the effectiveness of oral vitamin B12 for the treatment of pernicious anemia, the recommended dosage, and the required frequency of laboratory test and clinical monitoring. Relevant articles were identified by PubMed search from January 1, 1980 to March 31, 2016 and through hand search of relevant reference articles. Two randomized controlled trials, three prospective papers, one systematic review, and three clinical reviews fulfilled our inclusion criteria. We found that oral vitamin B12 replacement at 1000 μg daily was adequate to replace vitamin B12 levels in patients with pernicious anemia. We conclude that oral vitamin B12 is an effective alternative to vitamin B12 IM injections. Patients should be offered this alternative after an informed discussion on the advantages and disadvantages of both treatment options. |
X Demographics
The data shown below were collected from the profiles of 54 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 9 | 17% |
| United States | 9 | 17% |
| Canada | 4 | 7% |
| Spain | 3 | 6% |
| France | 2 | 4% |
| Ireland | 1 | 2% |
| New Zealand | 1 | 2% |
| Australia | 1 | 2% |
| Saudi Arabia | 1 | 2% |
| Other | 2 | 4% |
| Unknown | 21 | 39% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 41 | 76% |
| Practitioners (doctors, other healthcare professionals) | 7 | 13% |
| Scientists | 5 | 9% |
| Science communicators (journalists, bloggers, editors) | 1 | 2% |
Mendeley readers
The data shown below were compiled from readership statistics for 173 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| Unknown | 172 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 41 | 24% |
| Student > Master | 25 | 14% |
| Other | 14 | 8% |
| Student > Postgraduate | 9 | 5% |
| Lecturer | 8 | 5% |
| Other | 21 | 12% |
| Unknown | 55 | 32% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 43 | 25% |
| Nursing and Health Professions | 21 | 12% |
| Biochemistry, Genetics and Molecular Biology | 18 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 13 | 8% |
| Agricultural and Biological Sciences | 10 | 6% |
| Other | 7 | 4% |
| Unknown | 61 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 72. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 March 2024.
All research outputs
#606,359
of 25,820,938 outputs
Outputs from Frontiers in Medicine
#182
of 7,332 outputs
Outputs of similar age
#11,574
of 355,742 outputs
Outputs of similar age from Frontiers in Medicine
#1
of 12 outputs
Altmetric has tracked 25,820,938 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,332 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.6. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 355,742 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.