Title |
Liquid Biopsy in Non-Small Cell Lung Cancer
|
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Published in |
Frontiers in Medicine, December 2016
|
DOI | 10.3389/fmed.2016.00069 |
Pubmed ID | |
Authors |
Miguel A. Molina-Vila, Clara Mayo-de-las-Casas, Ana Giménez-Capitán, Núria Jordana-Ariza, Mónica Garzón, Ariadna Balada, Sergi Villatoro, Cristina Teixidó, Beatriz García-Peláez, Cristina Aguado, María José Catalán, Raquel Campos, Ana Pérez-Rosado, Jordi Bertran-Alamillo, Alejandro Martínez-Bueno, María-de-los-Llanos Gil, María González-Cao, Xavier González, Daniela Morales-Espinosa, Santiago Viteri, Niki Karachaliou, Rafael Rosell |
Abstract |
Liquid biopsy analyses are already incorporated in the routine clinical practice in many hospitals and oncology departments worldwide, improving the selection of treatments and monitoring of lung cancer patients. Although they have not yet reached its full potential, liquid biopsy-based tests will soon be as widespread as "standard" biopsies and imaging techniques, offering invaluable diagnostic, prognostic, and predictive information. This review summarizes the techniques available for the isolation and analysis of circulating free DNA and RNA, exosomes, tumor-educated platelets, and circulating tumor cells from the blood of cancer patients, presents the methodological challenges associated with each of these materials, and discusses the clinical applications of liquid biopsy testing in lung cancer. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Switzerland | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Germany | 1 | <1% |
Brazil | 1 | <1% |
Unknown | 117 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 25 | 21% |
Student > Ph. D. Student | 19 | 16% |
Student > Master | 10 | 8% |
Student > Doctoral Student | 9 | 8% |
Student > Bachelor | 9 | 8% |
Other | 23 | 19% |
Unknown | 24 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 36 | 30% |
Biochemistry, Genetics and Molecular Biology | 33 | 28% |
Agricultural and Biological Sciences | 11 | 9% |
Computer Science | 4 | 3% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 2% |
Other | 8 | 7% |
Unknown | 25 | 21% |