You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
microRNA in Cardiovascular Aging and Age-Related Cardiovascular Diseases
|
|---|---|
| Published in |
Frontiers in Medicine, June 2017
|
| DOI | 10.3389/fmed.2017.00074 |
| Pubmed ID | |
| Authors |
Claudio de Lucia, Klara Komici, Giulia Borghetti, Grazia Daniela Femminella, Leonardo Bencivenga, Alessandro Cannavo, Graziamaria Corbi, Nicola Ferrara, Steven R. Houser, Walter J. Koch, Giuseppe Rengo |
| Abstract |
Over the last decades, life expectancy has significantly increased although several chronic diseases persist in the population, with aging as the leading risk factor. Despite improvements in diagnosis and treatment, many elderlies suffer from cardiovascular problems that are much more frequent in an older, more fragile organism. In the long term, age-related cardiovascular diseases (CVDs) contribute to the decline of quality of life and ability to perform normal activities of daily living. microRNAs (miRNAs) are a class of small non-coding RNAs that regulate gene expression at the posttranscriptional level in both physiological and pathological conditions. In this review, we will focus on the role of miRNAs in aging and age-related CVDs as heart failure, hypertension, atherosclerosis, atrial fibrillation, and diabetes mellitus. miRNAs are key regulators of complex biological mechanisms, representing an exciting potential therapeutic target in CVDs. Moreover, one major challenge in geriatric medicine is to find reliable biomarkers for diagnosis, prognosis, and prediction of the response to specific drugs. miRNAs represent a very promising tool due to their stability in the circulation and unique signature in CVDs. However, further studies are needed to investigate their translational potential in the real clinical practice. |
X Demographics
The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 20% |
| Switzerland | 2 | 20% |
| Netherlands | 1 | 10% |
| Saudi Arabia | 1 | 10% |
| Curaçao | 1 | 10% |
| Italy | 1 | 10% |
| Unknown | 2 | 20% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 60% |
| Scientists | 2 | 20% |
| Practitioners (doctors, other healthcare professionals) | 2 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 110 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 110 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 29 | 26% |
| Student > Bachelor | 16 | 15% |
| Student > Ph. D. Student | 9 | 8% |
| Student > Master | 7 | 6% |
| Other | 6 | 5% |
| Other | 13 | 12% |
| Unknown | 30 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 30 | 27% |
| Medicine and Dentistry | 22 | 20% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 5% |
| Agricultural and Biological Sciences | 6 | 5% |
| Materials Science | 3 | 3% |
| Other | 8 | 7% |
| Unknown | 35 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 April 2019.
All research outputs
#6,978,745
of 25,703,943 outputs
Outputs from Frontiers in Medicine
#1,779
of 7,293 outputs
Outputs of similar age
#102,181
of 332,812 outputs
Outputs of similar age from Frontiers in Medicine
#17
of 70 outputs
Altmetric has tracked 25,703,943 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 7,293 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.6. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 332,812 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 70 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.