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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Platelets in Immune Response to Virus and Immunopathology of Viral Infections
|
|---|---|
| Published in |
Frontiers in Medicine, April 2018
|
| DOI | 10.3389/fmed.2018.00121 |
| Pubmed ID | |
| Authors |
Eugenio D. Hottz, Fernando A. Bozza, Patrícia T. Bozza |
| Abstract |
Platelets are essential effector cells in hemostasis. Aside from their role in coagulation, platelets are now recognized as major inflammatory cells with key roles in the innate and adaptive arms of the immune system. Activated platelets have key thromboinflammatory functions linking coagulation to immune responses in various infections, including in response to virus. Recent studies have revealed that platelets exhibit several pattern recognition receptors (PRR) including those from the toll-like receptor, NOD-like receptor, and C-type lectin receptor family and are first-line sentinels in detecting and responding to pathogens in the vasculature. Here, we review the main mechanisms of platelets interaction with viruses, including their ability to sustain viral infection and replication, their expression of specialized PRR, and activation of thromboinflammatory responses against viruses. Finally, we discuss the role of platelet-derived mediators and platelet interaction with vascular and immune cells in protective and pathophysiologic responses to dengue, influenza, and human immunodeficiency virus 1 infections. |
X Demographics
The data shown below were collected from the profiles of 57 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 14 | 25% |
| United Kingdom | 4 | 7% |
| India | 2 | 4% |
| Switzerland | 2 | 4% |
| Canada | 1 | 2% |
| Spain | 1 | 2% |
| Curaçao | 1 | 2% |
| Poland | 1 | 2% |
| Unknown | 31 | 54% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 45 | 79% |
| Practitioners (doctors, other healthcare professionals) | 8 | 14% |
| Scientists | 3 | 5% |
| Science communicators (journalists, bloggers, editors) | 1 | 2% |
Mendeley readers
The data shown below were compiled from readership statistics for 197 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 197 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 25 | 13% |
| Researcher | 21 | 11% |
| Student > Ph. D. Student | 20 | 10% |
| Student > Bachelor | 20 | 10% |
| Student > Doctoral Student | 13 | 7% |
| Other | 33 | 17% |
| Unknown | 65 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 46 | 23% |
| Immunology and Microbiology | 27 | 14% |
| Biochemistry, Genetics and Molecular Biology | 21 | 11% |
| Agricultural and Biological Sciences | 13 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 2% |
| Other | 14 | 7% |
| Unknown | 72 | 37% |
Attention Score in Context
This research output has an Altmetric Attention Score of 33. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 January 2022.
All research outputs
#1,246,112
of 25,806,763 outputs
Outputs from Frontiers in Medicine
#354
of 7,325 outputs
Outputs of similar age
#26,480
of 339,723 outputs
Outputs of similar age from Frontiers in Medicine
#6
of 105 outputs
Altmetric has tracked 25,806,763 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,325 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.6. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 339,723 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 105 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.