You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Tumor Heterogeneity in Primary Colorectal Cancer and Corresponding Metastases. Does the Apple Fall Far From the Tree?
|
|---|---|
| Published in |
Frontiers in Medicine, August 2018
|
| DOI | 10.3389/fmed.2018.00234 |
| Pubmed ID | |
| Authors |
Annika Blank, Daniel Edward Roberts, Heather Dawson, Inti Zlobec, Alessandro Lugli |
| Abstract |
Colorectal cancer harbors tremendous heterogeneity, with temporal and spatial differences in genetic mutations, epigenetic regulation, and tumor microenvironment. Analyzing the distribution and frequency of genetic, epigenetic, and microenvironment differences within a given tumor and between different sites of a metastatic tumor has been used as a powerful tool to investigate tumorigenesis, tumor progression, and to yield insight into various models of tumor development. A better understanding of tumor heterogeneity would have tremendous clinical relevance, which may manifest most clearly when genetic analyses to inform treatment decisions are performed on a very limited sample of a large tumor. This review summarizes the current concepts of tumor heterogeneity, with a focus on primary colorectal cancers and their corresponding metastases as well as potential clinical implications. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 125 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 125 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 28 | 22% |
| Researcher | 18 | 14% |
| Student > Bachelor | 16 | 13% |
| Student > Master | 13 | 10% |
| Student > Doctoral Student | 5 | 4% |
| Other | 11 | 9% |
| Unknown | 34 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 35 | 28% |
| Medicine and Dentistry | 30 | 24% |
| Agricultural and Biological Sciences | 10 | 8% |
| Immunology and Microbiology | 3 | 2% |
| Computer Science | 2 | 2% |
| Other | 10 | 8% |
| Unknown | 35 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 September 2023.
All research outputs
#3,101,109
of 24,393,299 outputs
Outputs from Frontiers in Medicine
#832
of 6,622 outputs
Outputs of similar age
#61,327
of 338,927 outputs
Outputs of similar age from Frontiers in Medicine
#16
of 85 outputs
Altmetric has tracked 24,393,299 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,622 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.9. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 338,927 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 85 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.