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MicroRNAs in HIV-1 infection: an integration of viral and cellular interaction at the genomic level

Overview of attention for article published in Frontiers in Microbiology, January 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (85th percentile)
  • High Attention Score compared to outputs of the same age and source (87th percentile)

Mentioned by

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3 X users
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2 patents

Citations

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16 Dimensions

Readers on

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38 Mendeley
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Title
MicroRNAs in HIV-1 infection: an integration of viral and cellular interaction at the genomic level
Published in
Frontiers in Microbiology, January 2012
DOI 10.3389/fmicb.2012.00306
Pubmed ID
Authors

Neil H. Tan Gana, Tomohiro Onuki, Ann Florence B. Victoriano, Takashi Okamoto

Abstract

The microRNA pathways govern complex interactions of the host and virus at the transcripts level that regulate cellular responses, viral replication and viral pathogenesis. As a group of single-stranded short non-coding ribonucleotides (ncRNAs), the microRNAs complement their messenger RNA (mRNA) targets to effect post-transcriptional or translational gene silencing. Previous studies showed the ability of human immunodeficiency virus 1 (HIV-1) to encode microRNAs which modify cellular defence mechanisms thus creating an environment favorable for viral invasion and replication. In corollary, cellular microRNAs were linked to the alteration of HIV-1 infection at different stages of replication and latency. As evidences further establish the regulatory involvement of both cellular and viral microRNA in HIV-1-host interactions, there is a necessity to organize this information. This paper would present current and emerging knowledge on these multi-dimensional interactions that may facilitate the design of microRNAs as effective antiretroviral reagents.

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X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 38 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 34%
Student > Bachelor 5 13%
Researcher 4 11%
Student > Doctoral Student 3 8%
Other 2 5%
Other 4 11%
Unknown 7 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 32%
Biochemistry, Genetics and Molecular Biology 7 18%
Immunology and Microbiology 5 13%
Medicine and Dentistry 2 5%
Computer Science 1 3%
Other 1 3%
Unknown 10 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 August 2017.
All research outputs
#4,079,076
of 22,675,759 outputs
Outputs from Frontiers in Microbiology
#4,135
of 24,472 outputs
Outputs of similar age
#34,912
of 244,088 outputs
Outputs of similar age from Frontiers in Microbiology
#39
of 317 outputs
Altmetric has tracked 22,675,759 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 24,472 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 244,088 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 317 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.