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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Molecular Recognition of Paired Receptors in the Immune System
|
|---|---|
| Published in |
Frontiers in Microbiology, January 2012
|
| DOI | 10.3389/fmicb.2012.00429 |
| Pubmed ID | |
| Authors |
Kimiko Kuroki, Atsushi Furukawa, Katsumi Maenaka |
| Abstract |
Cell surface receptors are responsible for regulating cellular function on the front line, the cell membrane. Interestingly, accumulating evidence clearly reveals that the members of cell surface receptor families have very similar extracellular ligand-binding regions but opposite signaling systems, either inhibitory or stimulatory. These receptors are designated as paired receptors. Paired receptors often recognize not only physiological ligands but also non-self ligands, such as viral and bacterial products, to fight infections. In this review, we introduce several representative examples of paired receptors, focusing on two major structural superfamilies, the immunoglobulin-like and the C-type lectin-like receptors, and explain how these receptors distinguish self and non-self ligands to maintain homeostasis in the immune system. We further discuss the evolutionary aspects of these receptors as well as the potential drug targets for regulating diseases. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 115 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Montenegro | 1 | <1% |
| United Kingdom | 1 | <1% |
| French Polynesia | 1 | <1% |
| Unknown | 112 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 35 | 30% |
| Student > Ph. D. Student | 19 | 17% |
| Student > Bachelor | 10 | 9% |
| Student > Master | 10 | 9% |
| Student > Doctoral Student | 8 | 7% |
| Other | 17 | 15% |
| Unknown | 16 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 41 | 36% |
| Biochemistry, Genetics and Molecular Biology | 19 | 17% |
| Immunology and Microbiology | 13 | 11% |
| Medicine and Dentistry | 10 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 4% |
| Other | 8 | 7% |
| Unknown | 19 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 June 2022.
All research outputs
#4,570,934
of 22,663,969 outputs
Outputs from Frontiers in Microbiology
#4,627
of 24,439 outputs
Outputs of similar age
#39,879
of 244,051 outputs
Outputs of similar age from Frontiers in Microbiology
#48
of 318 outputs
Altmetric has tracked 22,663,969 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 24,439 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 244,051 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 318 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.