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ramR mutations affecting fluoroquinolone susceptibility in epidemic multidrug-resistant Salmonella enterica serovar Kentucky ST198

Overview of attention for article published in Frontiers in Microbiology, January 2013
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Title
ramR mutations affecting fluoroquinolone susceptibility in epidemic multidrug-resistant Salmonella enterica serovar Kentucky ST198
Published in
Frontiers in Microbiology, January 2013
DOI 10.3389/fmicb.2013.00213
Pubmed ID
Authors

Sylvie Baucheron, Simon Le Hello, Benoît Doublet, Etienne Giraud, François-Xavier Weill, Axel Cloeckaert

Abstract

A screening for non-target mutations affecting fluoroquinolone susceptibility was conducted in epidemic multidrug-resistant Salmonella enterica serovar Kentucky ST198. Among a panel of representative isolates (n = 27), covering the epidemic, only three showed distinct mutations in ramR resulting in enhanced expression of genes encoding the AcrAB-TolC efflux system and low increase in ciprofloxacin MIC. No mutations were detected in other regulatory regions of this efflux system. Ciprofloxacin resistance in serovar Kentucky ST198 is thus currently mainly due to multiple target gene mutations.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Denmark 1 4%
Unknown 24 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 20%
Student > Master 4 16%
Student > Bachelor 4 16%
Other 2 8%
Researcher 2 8%
Other 1 4%
Unknown 7 28%
Readers by discipline Count As %
Agricultural and Biological Sciences 5 20%
Biochemistry, Genetics and Molecular Biology 3 12%
Veterinary Science and Veterinary Medicine 2 8%
Immunology and Microbiology 2 8%
Medicine and Dentistry 2 8%
Other 2 8%
Unknown 9 36%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 July 2013.
All research outputs
#20,196,821
of 22,715,151 outputs
Outputs from Frontiers in Microbiology
#22,142
of 24,551 outputs
Outputs of similar age
#248,768
of 280,748 outputs
Outputs of similar age from Frontiers in Microbiology
#264
of 407 outputs
Altmetric has tracked 22,715,151 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 24,551 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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