Title |
Biotic acts of antibiotics
|
---|---|
Published in |
Frontiers in Microbiology, January 2013
|
DOI | 10.3389/fmicb.2013.00241 |
Pubmed ID | |
Authors |
Rustam I. Aminov |
Abstract |
Biological functions of antibiotics are not limited to killing. The most likely function of antibiotics in natural microbial ecosystems is signaling. Does this signaling function of antibiotics also extend to the eukaryotic - in particular mammalian - cells? In this review, the host modulating properties of three classes of antibiotics (macrolides, tetracyclines, and β-lactams) will be briefly discussed. Antibiotics can be effective in treatment of a broad spectrum of diseases and pathological conditions other than those of infectious etiology and, in this capacity, may find widespread applications beyond the intended antimicrobial use. This use, however, should not compromise the primary function antibiotics are used for. The biological background for this inter-kingdom signaling is also discussed. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Switzerland | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 2 | 67% |
Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 1 | <1% |
Israel | 1 | <1% |
United Kingdom | 1 | <1% |
Spain | 1 | <1% |
Japan | 1 | <1% |
Unknown | 140 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 25 | 17% |
Researcher | 18 | 12% |
Student > Ph. D. Student | 13 | 9% |
Student > Master | 11 | 8% |
Other | 10 | 7% |
Other | 32 | 22% |
Unknown | 36 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 33 | 23% |
Agricultural and Biological Sciences | 24 | 17% |
Biochemistry, Genetics and Molecular Biology | 14 | 10% |
Immunology and Microbiology | 9 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 9 | 6% |
Other | 19 | 13% |
Unknown | 37 | 26% |