Title |
The factors affecting effectiveness of treatment in phages therapy
|
---|---|
Published in |
Frontiers in Microbiology, January 2014
|
DOI | 10.3389/fmicb.2014.00051 |
Pubmed ID | |
Authors |
Mai Huong Ly-Chatain |
Abstract |
In recent years, the use of lytic bacteriophages as antimicrobial agents controlling pathogenic bacteria has appeared as a promising new alternative strategy in the face of growing antibiotic resistance which has caused problems in many fields including medicine, veterinary medicine, and aquaculture. The use of bacteriophages has numerous advantages over traditional antimicrobials. The effectiveness of phage applications in fighting against pathogenic bacteria depends on several factors such as the bacteriophages/target bacteria ratio, the mode and moment of treatment, environmental conditions (pH, temperature...), the neutralization of phage and accessibility to target bacteria, amongst others. This report presents these factors and the challenges involved in developing phage therapy applications. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 29% |
Saudi Arabia | 1 | 14% |
Switzerland | 1 | 14% |
United States | 1 | 14% |
Unknown | 2 | 29% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 6 | 86% |
Members of the public | 1 | 14% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | <1% |
India | 1 | <1% |
Nepal | 1 | <1% |
Denmark | 1 | <1% |
United Kingdom | 1 | <1% |
Unknown | 458 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 77 | 17% |
Student > Ph. D. Student | 73 | 16% |
Student > Master | 64 | 14% |
Researcher | 42 | 9% |
Student > Doctoral Student | 22 | 5% |
Other | 57 | 12% |
Unknown | 129 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 119 | 26% |
Biochemistry, Genetics and Molecular Biology | 73 | 16% |
Immunology and Microbiology | 45 | 10% |
Veterinary Science and Veterinary Medicine | 18 | 4% |
Environmental Science | 13 | 3% |
Other | 55 | 12% |
Unknown | 141 | 30% |