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The lack of a big picture in tuberculosis: the clinical point of view, the problems of experimental modeling and immunomodulation. The factors we should consider when designing novel treatment…

Overview of attention for article published in Frontiers in Microbiology, January 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (81st percentile)
  • Good Attention Score compared to outputs of the same age and source (78th percentile)

Mentioned by

twitter
5 X users
wikipedia
1 Wikipedia page

Readers on

mendeley
63 Mendeley
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Title
The lack of a big picture in tuberculosis: the clinical point of view, the problems of experimental modeling and immunomodulation. The factors we should consider when designing novel treatment strategies
Published in
Frontiers in Microbiology, January 2014
DOI 10.3389/fmicb.2014.00055
Pubmed ID
Authors

Cristina Vilaplana, Pere-Joan Cardona

Abstract

This short review explores the large gap between clinical issues and basic science, and suggests why tuberculosis research should focus on redirect the immune system and not only on eradicating Mycobacterium tuberculosis bacillus. Along the manuscript, several concepts involved in human tuberculosis are explored in order to understand the big picture, including infection and disease dynamics, animal modeling, liquefaction, inflammation and immunomodulation. Scientists should take into account all these factors in order to answer questions with clinical relevance. Moreover, the inclusion of the concept of a strong inflammatory response being required in order to develop cavitary tuberculosis disease opens a new field for developing new therapeutic and prophylactic tools in which destruction of the bacilli may not necessarily be the final goal.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 2%
Denmark 1 2%
Canada 1 2%
Unknown 60 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 19%
Student > Ph. D. Student 9 14%
Student > Bachelor 8 13%
Student > Master 7 11%
Professor 4 6%
Other 9 14%
Unknown 14 22%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 24%
Medicine and Dentistry 12 19%
Immunology and Microbiology 7 11%
Engineering 3 5%
Biochemistry, Genetics and Molecular Biology 2 3%
Other 7 11%
Unknown 17 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 July 2014.
All research outputs
#4,541,100
of 22,743,667 outputs
Outputs from Frontiers in Microbiology
#4,556
of 24,608 outputs
Outputs of similar age
#55,106
of 305,223 outputs
Outputs of similar age from Frontiers in Microbiology
#19
of 87 outputs
Altmetric has tracked 22,743,667 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 24,608 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 305,223 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 87 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 78% of its contemporaries.