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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Effect of methylglyoxal on multidrug-resistant Pseudomonas aeruginosa
|
|---|---|
| Published in |
Frontiers in Microbiology, April 2014
|
| DOI | 10.3389/fmicb.2014.00180 |
| Pubmed ID | |
| Authors |
Katsuhiko Hayashi, Aiko Fukushima, Mitsuko Hayashi-Nishino, Kunihiko Nishino |
| Abstract |
Honey has a complex chemistry, and its broad-spectrum antimicrobial activity varies with floral source, climate, and harvesting conditions. Methylglyoxal was identified as the dominant antibacterial component of manuka honey. Although it has been known that methylglyoxal has antibacterial activity against gram-positive bacteria, including methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus, there is not much information describing its activity against gram-negative bacteria. In this study, we report the effect of methylglyoxal against multidrug-resistant Pseudomonas aeruginosa (MDRP) using 53 clinically isolated strains. We also assessed the effect of deleting the five multidrug efflux systems in P. aeruginosa, as well as the efflux systems in Escherichia coli and Salmonella enterica serovar Typhimurium, on MICs of methylglyoxal. Our results indicate that methylglyoxal inhibits the growth of MDRP at concentrations of 128-512 μg/ml (1.7-7.1 mM) and is not recognized by drug efflux systems. |
X Demographics
The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 3 | 38% |
| United States | 2 | 25% |
| Switzerland | 1 | 13% |
| Unknown | 2 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 5 | 63% |
| Members of the public | 2 | 25% |
| Practitioners (doctors, other healthcare professionals) | 1 | 13% |
Mendeley readers
The data shown below were compiled from readership statistics for 80 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Czechia | 1 | 1% |
| Unknown | 79 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 19 | 24% |
| Student > Master | 13 | 16% |
| Researcher | 11 | 14% |
| Student > Ph. D. Student | 5 | 6% |
| Other | 4 | 5% |
| Other | 12 | 15% |
| Unknown | 16 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 18 | 23% |
| Medicine and Dentistry | 10 | 13% |
| Biochemistry, Genetics and Molecular Biology | 9 | 11% |
| Immunology and Microbiology | 9 | 11% |
| Chemistry | 5 | 6% |
| Other | 8 | 10% |
| Unknown | 21 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 April 2019.
All research outputs
#6,777,642
of 22,753,345 outputs
Outputs from Frontiers in Microbiology
#6,872
of 24,627 outputs
Outputs of similar age
#65,121
of 226,127 outputs
Outputs of similar age from Frontiers in Microbiology
#49
of 171 outputs
Altmetric has tracked 22,753,345 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 24,627 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,127 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 171 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.