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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The activity of Nef on HIV-1 infectivity
|
|---|---|
| Published in |
Frontiers in Microbiology, May 2014
|
| DOI | 10.3389/fmicb.2014.00232 |
| Pubmed ID | |
| Authors |
Stéphane Basmaciogullari, Massimo Pizzato |
| Abstract |
The replication and pathogenicity of lentiviruses is crucially modulated by "auxiliary proteins" which are expressed in addition to the canonical retroviral ORFs gag, pol, and env. Strategies to inhibit the activity of such proteins are often sought and proposed as possible additions to increase efficacy of the traditional antiretroviral therapy. This requires the acquisition of an in-depth knowledge of the molecular mechanisms underlying their function. The Nef auxiliary protein is expressed uniquely by primate lentiviruses and plays an important role in virus replication in vivo and in the onset of AIDS. Among its several activities Nef enhances the intrinsic infectivity of progeny virions through a mechanism which remains today enigmatic. Here we review the current knowledge surrounding such activity and we discuss its possible role in HIV biology. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 187 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | <1% |
| Switzerland | 1 | <1% |
| Netherlands | 1 | <1% |
| Brazil | 1 | <1% |
| United Kingdom | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 181 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 45 | 24% |
| Student > Master | 32 | 17% |
| Student > Bachelor | 27 | 14% |
| Researcher | 21 | 11% |
| Student > Doctoral Student | 7 | 4% |
| Other | 16 | 9% |
| Unknown | 39 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 46 | 25% |
| Agricultural and Biological Sciences | 42 | 22% |
| Immunology and Microbiology | 39 | 21% |
| Medicine and Dentistry | 8 | 4% |
| Environmental Science | 2 | 1% |
| Other | 8 | 4% |
| Unknown | 42 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 May 2014.
All research outputs
#20,230,558
of 22,756,196 outputs
Outputs from Frontiers in Microbiology
#22,219
of 24,628 outputs
Outputs of similar age
#191,910
of 226,286 outputs
Outputs of similar age from Frontiers in Microbiology
#148
of 179 outputs
Altmetric has tracked 22,756,196 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 24,628 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,286 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 179 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.