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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Stress responses in flavivirus-infected cells: activation of unfolded protein response and autophagy
|
|---|---|
| Published in |
Frontiers in Microbiology, June 2014
|
| DOI | 10.3389/fmicb.2014.00266 |
| Pubmed ID | |
| Authors |
Ana-Belén Blázquez, Estela Escribano-Romero, Teresa Merino-Ramos, Juan-Carlos Saiz, Miguel A. Martín-Acebes |
| Abstract |
The Flavivirus is a genus of RNA viruses that includes multiple long known human, animal, and zoonotic pathogens such as Dengue virus, yellow fever virus, West Nile virus, or Japanese encephalitis virus, as well as other less known viruses that represent potential threats for human and animal health such as Usutu or Zika viruses. Flavivirus replication is based on endoplasmic reticulum-derived structures. Membrane remodeling and accumulation of viral factors induce endoplasmic reticulum stress that results in activation of a cellular signaling response termed unfolded protein response (UPR), which can be modulated by the viruses for their own benefit. Concomitant with the activation of the UPR, an upregulation of the autophagic pathway in cells infected with different flaviviruses has also been described. This review addresses the current knowledge of the relationship between endoplasmic reticulum stress, UPR, and autophagy in flavivirus-infected cells and the growing evidences for an involvement of these cellular pathways in the replication and pathogenesis of these viruses. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| India | 1 | 20% |
| Chile | 1 | 20% |
| United States | 1 | 20% |
| Switzerland | 1 | 20% |
| Unknown | 1 | 20% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 60% |
| Practitioners (doctors, other healthcare professionals) | 1 | 20% |
| Scientists | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 275 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 1% |
| Brazil | 3 | 1% |
| Germany | 2 | <1% |
| Switzerland | 1 | <1% |
| France | 1 | <1% |
| Canada | 1 | <1% |
| India | 1 | <1% |
| Unknown | 263 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 52 | 19% |
| Student > Ph. D. Student | 48 | 17% |
| Student > Bachelor | 39 | 14% |
| Student > Master | 31 | 11% |
| Student > Doctoral Student | 20 | 7% |
| Other | 48 | 17% |
| Unknown | 37 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 68 | 25% |
| Biochemistry, Genetics and Molecular Biology | 45 | 16% |
| Medicine and Dentistry | 31 | 11% |
| Immunology and Microbiology | 27 | 10% |
| Chemistry | 16 | 6% |
| Other | 37 | 13% |
| Unknown | 51 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 February 2016.
All research outputs
#13,542,652
of 23,577,654 outputs
Outputs from Frontiers in Microbiology
#10,117
of 26,068 outputs
Outputs of similar age
#109,573
of 229,704 outputs
Outputs of similar age from Frontiers in Microbiology
#81
of 170 outputs
Altmetric has tracked 23,577,654 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 26,068 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one has gotten more attention than average, scoring higher than 60% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 229,704 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.
We're also able to compare this research output to 170 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.