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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Membrane binding and bending in Ebola VP40 assembly and egress
|
|---|---|
| Published in |
Frontiers in Microbiology, January 2014
|
| DOI | 10.3389/fmicb.2014.00300 |
| Pubmed ID | |
| Authors |
Robert V. Stahelin |
| Abstract |
Lipid-enveloped viruses contain a lipid bilayer coat that protects their genome and helps to facilitate entry into the host cell. Filoviruses are lipid-enveloped viruses that have up to 90% clinical fatality and include Marbug (MARV) and Ebola (EBOV). These pleomorphic filamentous viruses enter the host cell through their membrane-embedded glycoprotein and then replicate using just seven genes encoded in their negative-sense RNA genome. EBOV budding occurs from the inner leaflet of the plasma membrane (PM) and is driven by the matrix protein VP40, which is the most abundantly expressed protein of the virus. VP40 expressed in mammalian cells alone can trigger budding of filamentous virus-like particles (VLPs) that are nearly indistinguishable from authentic EBOV. VP40, such as matrix proteins from other viruses, has been shown to bind anionic lipid membranes. However, how VP40 selectively interacts with the inner leaflet of the PM and assembles into a filamentous lipid enveloped particle is mostly unknown. This article describes what is known regarding VP40 membrane interactions and what answers will fill the gaps. |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 14% |
| Switzerland | 1 | 14% |
| Unknown | 5 | 71% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 4 | 57% |
| Members of the public | 3 | 43% |
Mendeley readers
The data shown below were compiled from readership statistics for 174 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 1% |
| Portugal | 1 | <1% |
| Netherlands | 1 | <1% |
| Ireland | 1 | <1% |
| Chile | 1 | <1% |
| Australia | 1 | <1% |
| Italy | 1 | <1% |
| Unknown | 166 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 37 | 21% |
| Student > Bachelor | 33 | 19% |
| Student > Master | 22 | 13% |
| Researcher | 20 | 11% |
| Other | 9 | 5% |
| Other | 30 | 17% |
| Unknown | 23 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 63 | 36% |
| Biochemistry, Genetics and Molecular Biology | 32 | 18% |
| Medicine and Dentistry | 20 | 11% |
| Chemistry | 7 | 4% |
| Physics and Astronomy | 5 | 3% |
| Other | 21 | 12% |
| Unknown | 26 | 15% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 January 2016.
All research outputs
#4,689,563
of 22,757,541 outputs
Outputs from Frontiers in Microbiology
#4,815
of 24,635 outputs
Outputs of similar age
#56,904
of 305,260 outputs
Outputs of similar age from Frontiers in Microbiology
#20
of 87 outputs
Altmetric has tracked 22,757,541 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 24,635 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 305,260 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 87 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.