Title |
Maternal and congenital toxoplasmosis, currently available and novel therapies in horizon
|
---|---|
Published in |
Frontiers in Microbiology, July 2014
|
DOI | 10.3389/fmicb.2014.00385 |
Pubmed ID | |
Authors |
Helieh S. Oz |
Abstract |
Over one billion people worldwide are predicted to harbor Toxoplasma infection frequently with unknown lifelong health consequences. Toxoplasmosis is an important cause of foodborne, inflammatory illnesses, as well as congenital abnormalities. Ubiquitous Toxoplasma has a unique tropism for central nervous system with a mind-bugging effect and is transmitted sexually through semen. Currently available therapies are ineffective for persistent chronic disease and congenital toxoplasmosis or have severe side effects which may result in life-threatening complications. There is an urgent need for safe and effective therapies to eliminate or treat this cosmopolitan infectious and inflammatory disease. This investigation discusses pathogenesis of maternal and congenital toxoplasmosis, the currently available therapies in practice, and the experimental therapeutic modalities for promising future trials. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Switzerland | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Australia | 1 | <1% |
Unknown | 113 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 24 | 21% |
Researcher | 15 | 13% |
Student > Ph. D. Student | 14 | 12% |
Student > Doctoral Student | 9 | 8% |
Student > Postgraduate | 8 | 7% |
Other | 20 | 18% |
Unknown | 24 | 21% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 26 | 23% |
Agricultural and Biological Sciences | 19 | 17% |
Biochemistry, Genetics and Molecular Biology | 10 | 9% |
Immunology and Microbiology | 10 | 9% |
Veterinary Science and Veterinary Medicine | 5 | 4% |
Other | 16 | 14% |
Unknown | 28 | 25% |