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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Next-generation sequencing approach for connecting secondary metabolites to biosynthetic gene clusters in fungi
|
|---|---|
| Published in |
Frontiers in Microbiology, January 2015
|
| DOI | 10.3389/fmicb.2014.00774 |
| Pubmed ID | |
| Authors |
Ralph A. Cacho, Yi Tang, Yit-Heng Chooi |
| Abstract |
Genomics has revolutionized the research on fungal secondary metabolite (SM) biosynthesis. To elucidate the molecular and enzymatic mechanisms underlying the biosynthesis of a specific SM compound, the important first step is often to find the genes that responsible for its synthesis. The accessibility to fungal genome sequences allows the bypass of the cumbersome traditional library construction and screening approach. The advance in next-generation sequencing (NGS) technologies have further improved the speed and reduced the cost of microbial genome sequencing in the past few years, which has accelerated the research in this field. Here, we will present an example work flow for identifying the gene cluster encoding the biosynthesis of SMs of interest using an NGS approach. We will also review the different strategies that can be employed to pinpoint the targeted gene clusters rapidly by giving several examples stemming from our work. |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 14% |
| South Africa | 1 | 14% |
| Switzerland | 1 | 14% |
| Unknown | 4 | 57% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 57% |
| Scientists | 3 | 43% |
Mendeley readers
The data shown below were compiled from readership statistics for 206 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 1% |
| Denmark | 1 | <1% |
| France | 1 | <1% |
| Unknown | 201 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 42 | 20% |
| Student > Master | 33 | 16% |
| Researcher | 31 | 15% |
| Student > Bachelor | 26 | 13% |
| Student > Postgraduate | 9 | 4% |
| Other | 38 | 18% |
| Unknown | 27 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 78 | 38% |
| Biochemistry, Genetics and Molecular Biology | 44 | 21% |
| Chemistry | 14 | 7% |
| Medicine and Dentistry | 6 | 3% |
| Immunology and Microbiology | 5 | 2% |
| Other | 22 | 11% |
| Unknown | 37 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 January 2022.
All research outputs
#7,758,411
of 24,885,505 outputs
Outputs from Frontiers in Microbiology
#8,074
of 28,434 outputs
Outputs of similar age
#100,953
of 364,900 outputs
Outputs of similar age from Frontiers in Microbiology
#79
of 273 outputs
Altmetric has tracked 24,885,505 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 28,434 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 364,900 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 273 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.