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Restriction modification systems as engines of diversity

Overview of attention for article published in Frontiers in Microbiology, June 2015
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Title
Restriction modification systems as engines of diversity
Published in
Frontiers in Microbiology, June 2015
DOI 10.3389/fmicb.2015.00528
Pubmed ID
Authors

Kim Sneppen, Szabolcs Semsey, Aswin S. N. Seshasayee, Sandeep Krishna

Abstract

Restriction modification (RM) systems provide protection against a broad spectrum of phages. However, the likelihood of a phage permanently bypassing this can be as high as 0.1 per infection (Korona et al., 1993) which makes for a relatively weak defense. Here we argue that, apart from providing such transient defenses, RM systems can facilitate long-term coexistence of many bacterial strains. We show that this diversity can be as large as the burst size of the phage but no larger-a curious correspondence between a number at the level of species and another number at the level of individuals. Such a highly diverse and stably coexisting ecosystem is robust to substantial variation in both bacterial growth rates and strength of their RM systems, which might be one reason why quite weak RM systems exist in the wild.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 69 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Malaysia 1 1%
France 1 1%
Egypt 1 1%
Unknown 66 96%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 16 23%
Student > Master 13 19%
Student > Ph. D. Student 12 17%
Researcher 6 9%
Student > Doctoral Student 3 4%
Other 8 12%
Unknown 11 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 26 38%
Biochemistry, Genetics and Molecular Biology 16 23%
Physics and Astronomy 6 9%
Immunology and Microbiology 5 7%
Medicine and Dentistry 2 3%
Other 3 4%
Unknown 11 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 May 2017.
All research outputs
#14,810,408
of 22,803,211 outputs
Outputs from Frontiers in Microbiology
#13,781
of 24,751 outputs
Outputs of similar age
#148,074
of 267,789 outputs
Outputs of similar age from Frontiers in Microbiology
#199
of 390 outputs
Altmetric has tracked 22,803,211 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 24,751 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 267,789 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 390 others from the same source and published within six weeks on either side of this one. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.