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Regulation of lung immunity and host defense by the intestinal microbiota

Overview of attention for article published in Frontiers in Microbiology, October 2015
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (98th percentile)

Mentioned by

news
4 news outlets
blogs
1 blog
policy
2 policy sources
twitter
30 X users
facebook
5 Facebook pages

Readers on

mendeley
414 Mendeley
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Title
Regulation of lung immunity and host defense by the intestinal microbiota
Published in
Frontiers in Microbiology, October 2015
DOI 10.3389/fmicb.2015.01085
Pubmed ID
Authors

Derrick R. Samuelson, David A. Welsh, Judd E. Shellito

Abstract

Every year in the United States approximately 200,000 people die from pulmonary infections, such as influenza and pneumonia, or from lung disease that is exacerbated by pulmonary infection. In addition, respiratory diseases such as, asthma, affect 300 million people worldwide. Therefore, understanding the mechanistic basis for host defense against infection and regulation of immune processes involved in asthma are crucial for the development of novel therapeutic strategies. The identification, characterization, and manipulation of immune regulatory networks in the lung represents one of the biggest challenges in treatment of lung associated disease. Recent evidence suggests that the gastrointestinal (GI) microbiota plays a key role in immune adaptation and initiation in the GI tract as well as at other distal mucosal sites, such as the lung. This review explores the current research describing the role of the GI microbiota in the regulation of pulmonary immune responses. Specific focus is given to understanding how intestinal "dysbiosis" affects lung health.

X Demographics

X Demographics

The data shown below were collected from the profiles of 30 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 414 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 <1%
United States 1 <1%
Czechia 1 <1%
Thailand 1 <1%
Unknown 410 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 75 18%
Student > Ph. D. Student 63 15%
Student > Master 53 13%
Student > Bachelor 38 9%
Student > Doctoral Student 25 6%
Other 66 16%
Unknown 94 23%
Readers by discipline Count As %
Agricultural and Biological Sciences 77 19%
Medicine and Dentistry 66 16%
Immunology and Microbiology 62 15%
Biochemistry, Genetics and Molecular Biology 55 13%
Pharmacology, Toxicology and Pharmaceutical Science 8 2%
Other 41 10%
Unknown 105 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 63. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 October 2023.
All research outputs
#665,442
of 25,255,356 outputs
Outputs from Frontiers in Microbiology
#372
of 28,990 outputs
Outputs of similar age
#9,520
of 284,831 outputs
Outputs of similar age from Frontiers in Microbiology
#6
of 432 outputs
Altmetric has tracked 25,255,356 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 28,990 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 284,831 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 432 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.