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Heterologous xylose isomerase pathway and evolutionary engineering improve xylose utilization in Saccharomyces cerevisiae

Overview of attention for article published in Frontiers in Microbiology, October 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)
  • High Attention Score compared to outputs of the same age and source (83rd percentile)

Mentioned by

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3 X users
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2 patents

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81 Mendeley
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Title
Heterologous xylose isomerase pathway and evolutionary engineering improve xylose utilization in Saccharomyces cerevisiae
Published in
Frontiers in Microbiology, October 2015
DOI 10.3389/fmicb.2015.01165
Pubmed ID
Authors

Xin Qi, Jian Zha, Gao-Gang Liu, Weiwen Zhang, Bing-Zhi Li, Ying-Jin Yuan

Abstract

Xylose utilization is one key issue for the bioconversion of lignocelluloses. It is a promising approach to engineering heterologous pathway for xylose utilization in Saccharomyces cerevisiae. Here, we constructed a xylose-fermenting yeast SyBE001 through combinatorial fine-tuning the expression of XylA and endogenous XKS1. Additional overexpression of genes RKI1, RPE1, TKL1, and TAL1 in the non-oxidative pentose phosphate pathway (PPP) in SyBE001 increased the xylose consumption rate by 1.19-fold. By repetitive adaptation, the xylose utilization rate was further increased by ∼10-fold in the resultant strain SyBE003. Gene expression analysis identified a variety of genes with significantly changed expression in the PPP, glycolysis and the tricarboxylic acid cycle in SyBE003.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 81 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 1 1%
China 1 1%
Brazil 1 1%
Unknown 78 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 20%
Student > Bachelor 13 16%
Researcher 12 15%
Student > Master 11 14%
Student > Doctoral Student 5 6%
Other 10 12%
Unknown 14 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 34 42%
Biochemistry, Genetics and Molecular Biology 14 17%
Engineering 5 6%
Nursing and Health Professions 2 2%
Chemical Engineering 2 2%
Other 5 6%
Unknown 19 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 October 2022.
All research outputs
#4,208,421
of 23,549,388 outputs
Outputs from Frontiers in Microbiology
#4,155
of 26,030 outputs
Outputs of similar age
#56,085
of 284,841 outputs
Outputs of similar age from Frontiers in Microbiology
#69
of 436 outputs
Altmetric has tracked 23,549,388 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 26,030 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 284,841 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 436 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.