Title |
Extraintestinal Infections Caused by Non-toxigenic Vibrio cholerae non-O1/non-O139
|
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Published in |
Frontiers in Microbiology, February 2016
|
DOI | 10.3389/fmicb.2016.00144 |
Pubmed ID | |
Authors |
Goutam Chowdhury, Sangeeta Joshi, Sanjay Bhattacharya, Uma Sekar, Balaji Birajdar, Arpita Bhattacharyya, Sumio Shinoda, Thandavarayan Ramamurthy |
Abstract |
Vibrio cholerae is an aerobic, sucrose fermentative Gram-negative bacterium that generally prevails in the environment. Pathogenic V. cholerae is well-known as causative agent of acute diarrhea. Apart from enteric infections, V. cholerae may also cause other diseases. However, their role in causing extraintestinal infections is not fully known as it needs proper identification and evaluation. Four cases of extraintestinal infections due to V. cholerae non-O1/non-O139 have been investigated. The isolates were screened for phenotypic and genetic characteristics with reference to their major virulence genes. Serologically distinct isolates harbored rtx, msh, and hly but lacked enteric toxin encoding genes that are generally present in toxigenic V. cholerae. Timely detection of this organism can prevent fatalities in hospital settings. The underlying virulence potential of V. cholerae needs appropriate testing and intervention. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 2% |
Unknown | 54 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 6 | 11% |
Student > Postgraduate | 6 | 11% |
Researcher | 6 | 11% |
Student > Doctoral Student | 4 | 7% |
Student > Ph. D. Student | 4 | 7% |
Other | 11 | 20% |
Unknown | 18 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 10 | 18% |
Biochemistry, Genetics and Molecular Biology | 7 | 13% |
Nursing and Health Professions | 6 | 11% |
Immunology and Microbiology | 4 | 7% |
Engineering | 3 | 5% |
Other | 6 | 11% |
Unknown | 19 | 35% |