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The Mitogen-Activated Protein Kinase (MAPK) Pathway: Role in Immune Evasion by Trypanosomatids

Overview of attention for article published in Frontiers in Microbiology, February 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (76th percentile)
  • Good Attention Score compared to outputs of the same age and source (74th percentile)

Mentioned by

news
1 news outlet
twitter
2 X users

Citations

dimensions_citation
159 Dimensions

Readers on

mendeley
401 Mendeley
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Title
The Mitogen-Activated Protein Kinase (MAPK) Pathway: Role in Immune Evasion by Trypanosomatids
Published in
Frontiers in Microbiology, February 2016
DOI 10.3389/fmicb.2016.00183
Pubmed ID
Authors

Mercedes Soares-Silva, Flavia F. Diniz, Gabriela N. Gomes, Diana Bahia

Abstract

Leishmania spp. and Trypanosoma cruzi are the causative agents of leishmaniasis and Chagas disease, respectively, two neglected tropical diseases that affect about 25 million people worldwide. These parasites belong to the family Trypanosomatidae, and are both obligate intracellular parasites that manipulate host signaling pathways and the innate immune system to establish infection. Mitogen-activated protein kinases (MAPKs) are serine and threonine protein kinases that are highly conserved in eukaryotes, and are involved in signal transduction pathways that modulate physiological and pathophysiological cell responses. This mini-review highlights existing knowledge concerning the mechanisms that Leishmania spp. and T. cruzi have evolved to target the host's MAPK signaling pathways and highjack the immune response, and, in this manner, promote parasite maintenance in the host.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 401 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 <1%
Unknown 400 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 68 17%
Student > Ph. D. Student 67 17%
Student > Master 55 14%
Researcher 36 9%
Student > Doctoral Student 15 4%
Other 32 8%
Unknown 128 32%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 94 23%
Agricultural and Biological Sciences 45 11%
Immunology and Microbiology 26 6%
Medicine and Dentistry 26 6%
Pharmacology, Toxicology and Pharmaceutical Science 18 4%
Other 53 13%
Unknown 139 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 February 2023.
All research outputs
#4,871,631
of 24,302,917 outputs
Outputs from Frontiers in Microbiology
#4,761
of 27,472 outputs
Outputs of similar age
#71,270
of 303,551 outputs
Outputs of similar age from Frontiers in Microbiology
#131
of 515 outputs
Altmetric has tracked 24,302,917 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 27,472 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 303,551 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 515 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.