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Plasmodium falciparum Secretome in Erythrocyte and Beyond

Overview of attention for article published in Frontiers in Microbiology, February 2016
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Title
Plasmodium falciparum Secretome in Erythrocyte and Beyond
Published in
Frontiers in Microbiology, February 2016
DOI 10.3389/fmicb.2016.00194
Pubmed ID
Authors

Rani Soni, Drista Sharma, Tarun K Bhatt

Abstract

Plasmodium falciparum is the causative agent of deadly malaria disease. It is an intracellular eukaryote and completes its multi-stage life cycle spanning the two hosts viz, mosquito and human. In order to habituate within host environment, parasite conform several strategies to evade host immune responses such as surface antigen polymorphism or modulation of host immune system and it is mediated by secretion of proteins from parasite to the host erythrocyte and beyond, collectively known as, malaria secretome. In this review, we will discuss about the deployment of parasitic secretory protein in mechanism implicated for immune evasion, protein trafficking, providing virulence, changing permeability and cyto-adherence of infected erythrocyte. We will be covering the possibilities of developing malaria secretome as a drug/vaccine target. This gathered information will be worthwhile in depicting a well-organized picture for host-pathogen interplay during the malaria infection and may also provide some clues for the development of novel anti-malarial therapies.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 67 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 1 1%
Germany 1 1%
Unknown 65 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 19 28%
Student > Ph. D. Student 13 19%
Researcher 9 13%
Student > Bachelor 9 13%
Student > Doctoral Student 3 4%
Other 3 4%
Unknown 11 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 20 30%
Biochemistry, Genetics and Molecular Biology 14 21%
Immunology and Microbiology 7 10%
Medicine and Dentistry 6 9%
Engineering 2 3%
Other 4 6%
Unknown 14 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 March 2016.
All research outputs
#17,787,961
of 22,849,304 outputs
Outputs from Frontiers in Microbiology
#17,221
of 24,853 outputs
Outputs of similar age
#202,557
of 297,895 outputs
Outputs of similar age from Frontiers in Microbiology
#369
of 535 outputs
Altmetric has tracked 22,849,304 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 24,853 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one is in the 22nd percentile – i.e., 22% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 297,895 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 535 others from the same source and published within six weeks on either side of this one. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.