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DistAMo: A Web-Based Tool to Characterize DNA-Motif Distribution on Bacterial Chromosomes

Overview of attention for article published in Frontiers in Microbiology, March 2016
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Title
DistAMo: A Web-Based Tool to Characterize DNA-Motif Distribution on Bacterial Chromosomes
Published in
Frontiers in Microbiology, March 2016
DOI 10.3389/fmicb.2016.00283
Pubmed ID
Authors

Patrick Sobetzko, Lukas Jelonek, Marc Strickert, Wenxia Han, Alexander Goesmann, Torsten Waldminghaus

Abstract

Short DNA motifs are involved in a multitude of functions such as for example chromosome segregation, DNA replication or mismatch repair. Distribution of such motifs is often not random and the specific chromosomal pattern relates to the respective motif function. Computational approaches which quantitatively assess such chromosomal motif patterns are necessary. Here we present a new computer tool DistAMo (Distribution Analysis of DNA Motifs). The algorithm uses codon redundancy to calculate the relative abundance of short DNA motifs from single genes to entire chromosomes. Comparative genomics analyses of the GATC-motif distribution in γ-proteobacterial genomes using DistAMo revealed that (i) genes beside the replication origin are enriched in GATCs, (ii) genome-wide GATC distribution follows a distinct pattern, and (iii) genes involved in DNA replication and repair are enriched in GATCs. These features are specific for bacterial chromosomes encoding a Dam methyltransferase. The new software is available as a stand-alone or as an easy-to-use web-based server version at http://www.computational.bio.uni-giessen.de/distamo.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 1 3%
China 1 3%
Unknown 32 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 32%
Researcher 10 29%
Student > Master 4 12%
Professor 3 9%
Professor > Associate Professor 2 6%
Other 3 9%
Unknown 1 3%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 41%
Biochemistry, Genetics and Molecular Biology 12 35%
Computer Science 3 9%
Nursing and Health Professions 1 3%
Immunology and Microbiology 1 3%
Other 0 0%
Unknown 3 9%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 May 2016.
All research outputs
#15,313,489
of 22,856,968 outputs
Outputs from Frontiers in Microbiology
#15,141
of 24,862 outputs
Outputs of similar age
#177,508
of 299,532 outputs
Outputs of similar age from Frontiers in Microbiology
#346
of 549 outputs
Altmetric has tracked 22,856,968 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 24,862 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 299,532 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 549 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.