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Induced Bacterial Cross-Resistance toward Host Antimicrobial Peptides: A Worrying Phenomenon

Overview of attention for article published in Frontiers in Microbiology, March 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (73rd percentile)
  • Good Attention Score compared to outputs of the same age and source (72nd percentile)

Mentioned by

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12 X users

Citations

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57 Dimensions

Readers on

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87 Mendeley
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Title
Induced Bacterial Cross-Resistance toward Host Antimicrobial Peptides: A Worrying Phenomenon
Published in
Frontiers in Microbiology, March 2016
DOI 10.3389/fmicb.2016.00381
Pubmed ID
Authors

Osmel Fleitas, Octávio L. Franco

Abstract

Bacterial resistance to conventional antibiotics has reached alarming levels, threatening to return to the pre-antibiotic era. Therefore, the search for new antimicrobial compounds that overcome the resistance phenomenon has become a priority. Antimicrobial peptides (AMPs) appear as one of the most promising antibiotic medicines. However, in recent years several AMP-resistance mechanisms have been described. Moreover, the AMP-resistance phenomenon has become more complex due to its association with cross-resistance toward AMP effectors of the host innate immune system. In this context, the use of AMPs as a therapeutic option could be potentially hazardous, since bacteria could develop resistance toward our innate immune system. Here, we review the findings of major studies that deal with the AMP cross-resistance phenomenon.

X Demographics

X Demographics

The data shown below were collected from the profiles of 12 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 87 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 1%
Unknown 86 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 21%
Student > Bachelor 18 21%
Student > Master 14 16%
Researcher 11 13%
Student > Doctoral Student 4 5%
Other 9 10%
Unknown 13 15%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 20 23%
Agricultural and Biological Sciences 18 21%
Immunology and Microbiology 15 17%
Medicine and Dentistry 4 5%
Pharmacology, Toxicology and Pharmaceutical Science 3 3%
Other 10 11%
Unknown 17 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 May 2016.
All research outputs
#5,483,850
of 22,858,915 outputs
Outputs from Frontiers in Microbiology
#5,074
of 24,866 outputs
Outputs of similar age
#78,086
of 300,491 outputs
Outputs of similar age from Frontiers in Microbiology
#155
of 555 outputs
Altmetric has tracked 22,858,915 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 24,866 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 300,491 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 555 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.