↓ Skip to main content

Microencapsulation in Alginate and Chitosan Microgels to Enhance Viability of Bifidobacterium longum for Oral Delivery

Overview of attention for article published in Frontiers in Microbiology, April 2016
Altmetric Badge

About this Attention Score

  • Average Attention Score compared to outputs of the same age
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

twitter
5 X users

Readers on

mendeley
248 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Microencapsulation in Alginate and Chitosan Microgels to Enhance Viability of Bifidobacterium longum for Oral Delivery
Published in
Frontiers in Microbiology, April 2016
DOI 10.3389/fmicb.2016.00494
Pubmed ID
Authors

Timothy W. Yeung, Elif F. Üçok, Kendra A. Tiani, David J. McClements, David A. Sela

Abstract

Probiotic microorganisms are incorporated into a wide variety of foods, supplements, and pharmaceuticals to promote human health and wellness. However, maintaining bacterial cell viability during storage and gastrointestinal transit remains a challenge. Encapsulation of bifidobacteria within food-grade hydrogel particles potentially mitigates their sensitivity to environmental stresses. In this study, Bifidobacterium longum subspecies and strains were encapsulated in core-shell microgels consisting of an alginate core and a microgel shell. Encapsulated obligate anaerobes Bifidobacterium longum subsp. infantis and Bifidobacterium longum subsp. longum exhibited differences in viability in a strain-dependent manner, without a discernable relationship to subspecies lineage. This includes viability under aerobic storage conditions and modeled gastrointestinal tract conditions. Coating alginate microgels with chitosan did not improve viability compared to cells encapsulated in alginate microgels alone, suggesting that modifying the surface charge alone does not enhance delivery. Thus hydrogel beads have great potential for improving the stability and efficacy of bifidobacterial probiotics in various nutritional interventions.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 248 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Indonesia 1 <1%
United Kingdom 1 <1%
Mexico 1 <1%
Colombia 1 <1%
Unknown 244 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 52 21%
Student > Master 35 14%
Researcher 28 11%
Student > Bachelor 24 10%
Student > Doctoral Student 17 7%
Other 31 13%
Unknown 61 25%
Readers by discipline Count As %
Agricultural and Biological Sciences 53 21%
Biochemistry, Genetics and Molecular Biology 31 13%
Engineering 17 7%
Pharmacology, Toxicology and Pharmaceutical Science 13 5%
Chemistry 11 4%
Other 44 18%
Unknown 79 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 May 2016.
All research outputs
#15,164,620
of 25,364,603 outputs
Outputs from Frontiers in Microbiology
#12,210
of 29,275 outputs
Outputs of similar age
#158,359
of 313,313 outputs
Outputs of similar age from Frontiers in Microbiology
#277
of 554 outputs
Altmetric has tracked 25,364,603 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 29,275 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one has gotten more attention than average, scoring higher than 55% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,313 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 554 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.