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Anti-biofilm Activities from Resveratrol against Fusobacterium nucleatum

Overview of attention for article published in Frontiers in Microbiology, July 2016
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  • Above-average Attention Score compared to outputs of the same age and source (54th percentile)

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51 Mendeley
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Title
Anti-biofilm Activities from Resveratrol against Fusobacterium nucleatum
Published in
Frontiers in Microbiology, July 2016
DOI 10.3389/fmicb.2016.01065
Pubmed ID
Authors

Zhiyan He, Zhengwei Huang, Wei Zhou, Zisheng Tang, Rui Ma, Jingping Liang

Abstract

Fusobacterium nucleatum is a Gram-negative, anaerobic bacterium that plays an important role in dental plaque biofilm formation. In this study, we evaluate the effect of resveratrol, a phytoalexin compound, on F. nucleatum biofilm formation. The effects of different concentrations of resveratrol on biofilms formed on 96-well microtiter plates at different time points were determined by the MTT assay. The structures and thicknesses of the biofilm were observed by confocal laser scanning microscopy (CLSM), and gene expression was investigated by real-time PCR. The results showed that resveratrol at sub-MIC levels can significantly decrease biofilm formation, whereas it does not affect the bacterial growth rate. It was observed by CLSM images that the biofilm was visually decreased with increasing concentrations of resveratrol. Gene expression was down regulated in the biofilm in the presence of resveratrol. Our results revealed that resveratrol can effectively inhibit biofilm formation.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 51 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 18%
Student > Bachelor 5 10%
Student > Doctoral Student 4 8%
Student > Master 4 8%
Other 2 4%
Other 6 12%
Unknown 21 41%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 8 16%
Medicine and Dentistry 7 14%
Immunology and Microbiology 6 12%
Agricultural and Biological Sciences 4 8%
Pharmacology, Toxicology and Pharmaceutical Science 3 6%
Other 2 4%
Unknown 21 41%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 February 2022.
All research outputs
#13,096,714
of 23,206,358 outputs
Outputs from Frontiers in Microbiology
#9,257
of 25,472 outputs
Outputs of similar age
#180,838
of 356,280 outputs
Outputs of similar age from Frontiers in Microbiology
#224
of 499 outputs
Altmetric has tracked 23,206,358 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 25,472 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one has gotten more attention than average, scoring higher than 63% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 356,280 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 499 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.