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Dendritic Cells: A Double-Edged Sword in Immune Responses during Chagas Disease

Overview of attention for article published in Frontiers in Microbiology, July 2016
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Title
Dendritic Cells: A Double-Edged Sword in Immune Responses during Chagas Disease
Published in
Frontiers in Microbiology, July 2016
DOI 10.3389/fmicb.2016.01076
Pubmed ID
Authors

Natalia Gil-Jaramillo, Flávia N. Motta, Cecília B. F. Favali, Izabela M. D. Bastos, Jaime M. Santana

Abstract

Dendritic cells (DCs) are the most important member of the antigen presenting cells group due to their ability to recognize antigen at the infection site and their high specialized antigen internalization capacity. These cells have central role in connecting the innate and adaptive immune responses against Trypanosoma cruzi, the causative agent of Chagas disease. These first line defense cells modulate host immune response depending on type, maturation level, cytokine milieu and DC receptor involved in the interactions with T. cruzi, influencing the development of the disease clinic forms. Here, we present a review of DCs-T. cruzi interactions both in human and murine models, pointing out the parasite ability to manipulate DCs activity for the purpose of evading innate immune response and assuring its own survival and persistence.

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The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 80 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 80 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 17 21%
Student > Master 16 20%
Researcher 8 10%
Student > Ph. D. Student 8 10%
Student > Doctoral Student 6 8%
Other 13 16%
Unknown 12 15%
Readers by discipline Count As %
Immunology and Microbiology 24 30%
Biochemistry, Genetics and Molecular Biology 14 18%
Agricultural and Biological Sciences 12 15%
Medicine and Dentistry 7 9%
Veterinary Science and Veterinary Medicine 3 4%
Other 9 11%
Unknown 11 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 July 2016.
All research outputs
#13,782,977
of 22,880,691 outputs
Outputs from Frontiers in Microbiology
#11,242
of 24,908 outputs
Outputs of similar age
#196,346
of 355,133 outputs
Outputs of similar age from Frontiers in Microbiology
#236
of 486 outputs
Altmetric has tracked 22,880,691 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 24,908 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one has gotten more attention than average, scoring higher than 54% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 355,133 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 486 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.