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Complete Sequence of pEC012, a Multidrug-Resistant IncI1 ST71 Plasmid Carrying blaCTX-M-65, rmtB, fosA3, floR, and oqxAB in an Avian Escherichia coli ST117 Strain

Overview of attention for article published in Frontiers in Microbiology, July 2016
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Title
Complete Sequence of pEC012, a Multidrug-Resistant IncI1 ST71 Plasmid Carrying blaCTX-M-65, rmtB, fosA3, floR, and oqxAB in an Avian Escherichia coli ST117 Strain
Published in
Frontiers in Microbiology, July 2016
DOI 10.3389/fmicb.2016.01117
Pubmed ID
Authors

Yu-Shan Pan, Zhi-Yong Zong, Li Yuan, Xiang-Dang Du, Hui Huang, Xing-Hao Zhong, Gong-Zheng Hu

Abstract

A 139,622-bp IncI1 ST71 conjugative plasmid pEC012 from an avian Escherichia coli D-ST117 strain was sequenced, which carried five IS26-bracketed resistance modules: IS26-fosA3-orf1-orf2-Δorf3-IS26, IS26-fip-ΔISEcp1-bla CTX-M-65-IS903D-iroN-IS26, IS26-ΔtnpR-bla TEM-1-rmtB-IS26, IS26-oqxAB-IS26, and IS26-floR-aac(3)-IV-IS26. The backbone of pEC012 was similar to that of several other IncI1 ST71 plasmids: pV408, pM105, and pC271, but these plasmids had different arrangements of multidrug resistance region. In addition, the novel ISEc57 element was identified, which is in the IS21 family. The stepwise emergence of multi-resistance regions demonstrated the accumulation of different resistance determinants through homologous recombination. To the best of our knowledge, this is the first study to identify a multidrug-resistant IncI1 ST71 plasmid carrying bla CTX-M-65, rmtB, fosA3, floR, and oqxAB in an avian E. coli ST117 strain.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 1 5%
Unknown 21 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 27%
Student > Master 4 18%
Student > Postgraduate 2 9%
Student > Ph. D. Student 2 9%
Student > Doctoral Student 1 5%
Other 2 9%
Unknown 5 23%
Readers by discipline Count As %
Agricultural and Biological Sciences 6 27%
Immunology and Microbiology 5 23%
Medicine and Dentistry 3 14%
Biochemistry, Genetics and Molecular Biology 2 9%
Unknown 6 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 July 2016.
All research outputs
#20,335,770
of 22,880,691 outputs
Outputs from Frontiers in Microbiology
#22,505
of 24,911 outputs
Outputs of similar age
#317,191
of 363,150 outputs
Outputs of similar age from Frontiers in Microbiology
#422
of 492 outputs
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