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X Demographics
Mendeley readers
Attention Score in Context
| Title |
PSM-Mec—A Virulence Determinant that Connects Transcriptional Regulation, Virulence, and Antibiotic Resistance in Staphylococci
|
|---|---|
| Published in |
Frontiers in Microbiology, August 2016
|
| DOI | 10.3389/fmicb.2016.01293 |
| Pubmed ID | |
| Authors |
Li Qin, Joshua W. McCausland, Gordon Y. C. Cheung, Michael Otto |
| Abstract |
PSM-mec is a secreted virulence factor that belongs to the phenol-soluble modulin (PSM) family of amphipathic, alpha-helical peptide toxins produced by Staphylococcus species. All known PSMs are core genome-encoded with the exception of PSM-mec, whose gene is found in specific sub-types of SCCmec methicillin resistance mobile genetic elements present in methicillin-resistant Staphylococcus aureus and coagulase-negative staphylococci. In addition to the cytolytic translational product, PSM-mec, the psm-mec locus encodes a regulatory RNA. In S. aureus, the psm-mec locus influences cytolytic capacity, methicillin resistance, biofilm formation, cell spreading, and the expression of other virulence factors, such as other PSMs, which results in a significant impact on immune evasion and disease. However, these effects are highly strain-dependent, which is possibly due to differences in PSM-mec peptide vs. psm-mec RNA-controlled effects. Here, we summarize the functional properties of PSM-mec and the psm-mec RNA molecule and their roles in staphylococcal pathogenesis and physiology. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 25% |
| Unknown | 3 | 75% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Scientists | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 81 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Chile | 1 | 1% |
| Brazil | 1 | 1% |
| Unknown | 79 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 23 | 28% |
| Researcher | 11 | 14% |
| Student > Bachelor | 11 | 14% |
| Student > Master | 10 | 12% |
| Student > Doctoral Student | 4 | 5% |
| Other | 10 | 12% |
| Unknown | 12 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 18 | 22% |
| Agricultural and Biological Sciences | 15 | 19% |
| Immunology and Microbiology | 13 | 16% |
| Medicine and Dentistry | 8 | 10% |
| Veterinary Science and Veterinary Medicine | 4 | 5% |
| Other | 6 | 7% |
| Unknown | 17 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 April 2019.
All research outputs
#2,882,527
of 22,886,568 outputs
Outputs from Frontiers in Microbiology
#2,599
of 24,928 outputs
Outputs of similar age
#52,390
of 343,739 outputs
Outputs of similar age from Frontiers in Microbiology
#74
of 422 outputs
Altmetric has tracked 22,886,568 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 24,928 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 343,739 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 422 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 82% of its contemporaries.