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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The Progress of Therapeutic Vaccination with Regard to Tuberculosis
|
|---|---|
| Published in |
Frontiers in Microbiology, September 2016
|
| DOI | 10.3389/fmicb.2016.01536 |
| Pubmed ID | |
| Authors |
Pere-Joan Cardona |
| Abstract |
A major problem with tuberculosis (TB) control is the long duration of drug therapy-both for latent and for active TB. Therapeutic vaccination has been postulated to improve this situation, and to this end there are several candidates already in clinical phases of development. These candidates follow two main designs, namely bacilli-directed therapy based on inactivated -whole or -fragmented bacillus (Mycobacterium w and RUTI) or fusion proteins that integrate non-replicating bacilli -related antigens (H56 vaccine), and host-directed therapy to reduce the tissue destruction. The administration of inactivated Mycobacterium vaccae prevents the "Koch phenomenon" response, and oral administration of heat-killed Mycobacterium manresensis prevents excessive neutrophilic infiltration of the lesions. This review also tries to explain the success of Mycobacterium tuberculosis by reviewing its evolution from infection to disease, and highlights the lack of a definitive understanding of the natural history of TB pathology and the need to improve our knowledge on TB immunology and pathogenesis. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 3 | 75% |
| Unknown | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 87 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 87 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 14 | 16% |
| Student > Ph. D. Student | 13 | 15% |
| Researcher | 12 | 14% |
| Student > Bachelor | 9 | 10% |
| Student > Postgraduate | 6 | 7% |
| Other | 8 | 9% |
| Unknown | 25 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 22 | 25% |
| Biochemistry, Genetics and Molecular Biology | 11 | 13% |
| Agricultural and Biological Sciences | 8 | 9% |
| Medicine and Dentistry | 6 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 3% |
| Other | 9 | 10% |
| Unknown | 28 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 January 2020.
All research outputs
#3,760,796
of 23,705,225 outputs
Outputs from Frontiers in Microbiology
#3,417
of 26,269 outputs
Outputs of similar age
#61,807
of 324,910 outputs
Outputs of similar age from Frontiers in Microbiology
#84
of 437 outputs
Altmetric has tracked 23,705,225 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 26,269 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 324,910 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 437 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.