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Azole Antifungal Resistance in Candida albicans and Emerging Non-albicans Candida Species

Overview of attention for article published in Frontiers in Microbiology, January 2017
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (98th percentile)

Mentioned by

news
22 news outlets
blogs
1 blog
twitter
8 X users

Readers on

mendeley
907 Mendeley
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Title
Azole Antifungal Resistance in Candida albicans and Emerging Non-albicans Candida Species
Published in
Frontiers in Microbiology, January 2017
DOI 10.3389/fmicb.2016.02173
Pubmed ID
Authors

Sarah G. Whaley, Elizabeth L. Berkow, Jeffrey M. Rybak, Andrew T. Nishimoto, Katherine S. Barker, P. David Rogers

Abstract

Within the limited antifungal armamentarium, the azole antifungals are the most frequent class used to treat Candida infections. Azole antifungals such as fluconazole are often preferred treatment for many Candida infections as they are inexpensive, exhibit limited toxicity, and are available for oral administration. There is, however, extensive documentation of intrinsic and developed resistance to azole antifungals among several Candida species. As the frequency of azole resistant Candida isolates in the clinical setting increases, it is essential to elucidate the mechanisms of such resistance in order to both preserve and improve upon the azole class of antifungals for the treatment of Candida infections. This review examines azole resistance in infections caused by C. albicans as well as the emerging non-albicans Candida species C. parapsilosis, C. tropicalis, C. krusei, and C. glabrata and in particular, describes the current understanding of molecular basis of azole resistance in these fungal species.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 907 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 <1%
Unknown 906 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 137 15%
Student > Master 129 14%
Student > Ph. D. Student 92 10%
Researcher 66 7%
Student > Doctoral Student 49 5%
Other 134 15%
Unknown 300 33%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 153 17%
Immunology and Microbiology 114 13%
Agricultural and Biological Sciences 86 9%
Medicine and Dentistry 84 9%
Pharmacology, Toxicology and Pharmaceutical Science 48 5%
Other 88 10%
Unknown 334 37%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 189. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 November 2019.
All research outputs
#176,888
of 23,005,189 outputs
Outputs from Frontiers in Microbiology
#92
of 25,097 outputs
Outputs of similar age
#4,380
of 422,503 outputs
Outputs of similar age from Frontiers in Microbiology
#4
of 394 outputs
Altmetric has tracked 23,005,189 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 25,097 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 422,503 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 394 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.