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Mendeley readers
Attention Score in Context
| Title |
Phytochemical Characterization of Terminalia catappa Linn. Extracts and Their antifungal Activities against Candida spp.
|
|---|---|
| Published in |
Frontiers in Microbiology, April 2017
|
| DOI | 10.3389/fmicb.2017.00595 |
| Pubmed ID | |
| Authors |
Analucia G. Terças, Andrea de Souza Monteiro, Eduardo B. Moffa, Julliana R. A. dos Santos, Eduardo M. de Sousa, Anna R. B. Pinto, Paola C. da Silva Costa, Antonio C. R. Borges, Luce M. B. Torres, Allan K. D. Barros Filho, Elizabeth S. Fernandes, Cristina de Andrade Monteiro |
| Abstract |
Terminalia catappa Linn bark is used to treat dysentery by various populations in Southeast Asian countries, and its leaves have also been used in traditional medicine to treat hepatitis in India and the Philippines. Here, the antifungal actions of crude hydro-alcoholic extract (TcHE) and fractions from T. catappa leaves were assessed via the agar diffusion and microdilution tests on Candida reference strains and clinical isolates from patients with acquired immunodeficiency syndrome (AIDS). Additionally, the potential cytotoxic effects of TcHE were assessed on cultured human peripheral blood mononuclear cells (PBMC). T. catappa fractions and sub-fractions were analyzed by gas chromatography coupled to mass spectrometry with electron impact (GC/MS/EI), high-performance liquid chromatography coupled to mass spectrometry "electrospray" ionization in positive mode (HPLC/MS/MS/ESI(+)) and hydrogen nuclear magnetic resonance ((1)HNMR). TcHE and its fractions were able to inhibit the growth of all tested Candida strains with the n-butanol (FBuOH) fraction presenting the best antifungal activity. Testing of different FBuOH sub-fractions (SF) showed that SF10 was the most active against Candida spp. Fractioning of SF10 demonstrated that 5 out of its 15 sub-fractions were active against Candida spp., with SF10.5 presenting the highest activity. Chemical analysis of SF10 detected hydrolysable tannins (punicalin, punicalagin), gallic acid and flavonoid C-glycosides. Overall, the results showed that T. catappa L. leaf extract, fractions and sub-fractions were antifungal against Candida spp. and may be useful to treat diseases caused by this fungus. |
Mendeley readers
The data shown below were compiled from readership statistics for 151 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Indonesia | 1 | <1% |
| Unknown | 150 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 19 | 13% |
| Student > Ph. D. Student | 15 | 10% |
| Student > Master | 13 | 9% |
| Researcher | 12 | 8% |
| Lecturer | 7 | 5% |
| Other | 16 | 11% |
| Unknown | 69 | 46% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 15 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 14 | 9% |
| Agricultural and Biological Sciences | 13 | 9% |
| Immunology and Microbiology | 8 | 5% |
| Biochemistry, Genetics and Molecular Biology | 6 | 4% |
| Other | 21 | 14% |
| Unknown | 74 | 49% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 April 2017.
All research outputs
#6,300,546
of 24,458,924 outputs
Outputs from Frontiers in Microbiology
#5,948
of 27,712 outputs
Outputs of similar age
#94,742
of 314,507 outputs
Outputs of similar age from Frontiers in Microbiology
#196
of 498 outputs
Altmetric has tracked 24,458,924 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 27,712 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 314,507 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 498 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 59% of its contemporaries.