Title |
Efficacy of (+)-Lariciresinol to Control Bacterial Growth of Staphylococcus aureus and Escherichia coli O157:H7
|
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Published in |
Frontiers in Microbiology, May 2017
|
DOI | 10.3389/fmicb.2017.00804 |
Pubmed ID | |
Authors |
Vivek K. Bajpai, Shruti Shukla, Woon K. Paek, Jeongheui Lim, Pradeep Kumar, Pankaj Kumar, MinKyun Na |
Abstract |
This study was undertaken to assess the antibacterial potential of a polyphenolic compound (+)-lariciresinol isolated from Rubia philippinensis against selected foodborne pathogens Staphylococcus aureus KCTC1621 and Escherichia coli O157:H7. (+)-Lariciresinol at the tested concentrations (250 μg/disk) evoked a significant antibacterial effect as a diameter of inhibition zones (12.1-14.9 mm) with minimum inhibitory concentration (MIC), and minimum bactericidal concentration values of 125-250 and 125-250 μg/mL, respectively. Furthermore, (+)-lariciresinol at MIC showed reduction in bacterial cell viabilities, efflux of potassium (K(+)) ions and release of 260 nm materials against E. coli O157:H7 and S. aureus KCTC1621. Moreover, deteriorated cell wall morphology of E. coli O157:H7 and S. aureus KCTC1621 cells treated with (+)-lariciresinol at MIC further confirmed its inhibitory effect against the tested pathogens, suggesting it to be an alternative means of antimicrobials. |
X Demographics
Geographical breakdown
Country | Count | As % |
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India | 1 | 25% |
Unknown | 3 | 75% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 75% |
Scientists | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 28 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 8 | 29% |
Student > Master | 6 | 21% |
Professor > Associate Professor | 2 | 7% |
Unspecified | 2 | 7% |
Student > Doctoral Student | 1 | 4% |
Other | 3 | 11% |
Unknown | 6 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 6 | 21% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 11% |
Chemistry | 3 | 11% |
Unspecified | 2 | 7% |
Biochemistry, Genetics and Molecular Biology | 2 | 7% |
Other | 4 | 14% |
Unknown | 8 | 29% |