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Azole Resistance in Aspergillus fumigatus: A Consequence of Antifungal Use in Agriculture?

Overview of attention for article published in Frontiers in Microbiology, June 2017
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Mentioned by

news
24 news outlets
blogs
3 blogs
twitter
11 X users
wikipedia
1 Wikipedia page

Citations

dimensions_citation
168 Dimensions

Readers on

mendeley
337 Mendeley
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Title
Azole Resistance in Aspergillus fumigatus: A Consequence of Antifungal Use in Agriculture?
Published in
Frontiers in Microbiology, June 2017
DOI 10.3389/fmicb.2017.01024
Pubmed ID
Authors

Sarah Berger, Yassine El Chazli, Ambrin F. Babu, Alix T. Coste

Abstract

Agricultural industry uses pesticides to optimize food production for the growing human population. A major issue for crops is fungal phytopathogens, which are treated mainly with azole fungicides. Azoles are also the main medical treatment in the management of Aspergillus diseases caused by ubiquitous fungi, such as Aspergillus fumigatus. However, epidemiological research demonstrated an increasing prevalence of azole-resistant strains in A. fumigatus. The main resistance mechanism is a combination of alterations in the gene cyp51A (TR34/L98H). Surprisingly, this mutation is not only found in patients receiving long-term azole therapy for chronic aspergillosis but also in azole naïve patients. This suggests an environmental route of resistance through the exposure of azole fungicides in agriculture. In this review, we report data from several studies that strongly suggest that agricultural azoles are responsible for medical treatment failure in azole-naïve patients in clinical settings.

X Demographics

X Demographics

The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 337 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
Unknown 336 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 58 17%
Student > Ph. D. Student 50 15%
Researcher 43 13%
Student > Master 41 12%
Student > Doctoral Student 11 3%
Other 35 10%
Unknown 99 29%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 58 17%
Agricultural and Biological Sciences 57 17%
Immunology and Microbiology 35 10%
Medicine and Dentistry 16 5%
Chemistry 16 5%
Other 39 12%
Unknown 116 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 220. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 September 2022.
All research outputs
#153,960
of 23,577,761 outputs
Outputs from Frontiers in Microbiology
#84
of 26,068 outputs
Outputs of similar age
#3,577
of 318,487 outputs
Outputs of similar age from Frontiers in Microbiology
#3
of 523 outputs
Altmetric has tracked 23,577,761 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 26,068 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 318,487 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 523 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.