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Dengue Virus Glycosylation: What Do We Know?

Overview of attention for article published in Frontiers in Microbiology, July 2017
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Mentioned by

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2 X users
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1 peer review site

Citations

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72 Dimensions

Readers on

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186 Mendeley
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Title
Dengue Virus Glycosylation: What Do We Know?
Published in
Frontiers in Microbiology, July 2017
DOI 10.3389/fmicb.2017.01415
Pubmed ID
Authors

Sally S. L. Yap, Terry Nguyen-Khuong, Pauline M. Rudd, Sylvie Alonso

Abstract

In many infectious diseases caused by either viruses or bacteria, pathogen glycoproteins play important roles during the infection cycle, ranging from entry to successful intracellular replication and host immune evasion. Dengue is no exception. Dengue virus glycoproteins, envelope protein (E) and non-structural protein 1 (NS1) are two popular sub-unit vaccine candidates. E protein on the virion surface is the major target of neutralizing antibodies. NS1 which is secreted during DENV infection has been shown to induce a variety of host responses through its binding to several host factors. However, despite their critical role in disease and protection, the glycosylated variants of these two proteins and their biological importance have remained understudied. In this review, we seek to provide a comprehensive summary of the current knowledge on protein glycosylation in DENV, and its role in virus biogenesis, host cell receptor interaction and disease pathogenesis.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 186 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 186 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 33 18%
Student > Master 27 15%
Student > Bachelor 25 13%
Researcher 25 13%
Student > Doctoral Student 10 5%
Other 14 8%
Unknown 52 28%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 46 25%
Agricultural and Biological Sciences 22 12%
Immunology and Microbiology 18 10%
Chemistry 12 6%
Medicine and Dentistry 9 5%
Other 22 12%
Unknown 57 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 August 2017.
All research outputs
#14,357,979
of 22,992,311 outputs
Outputs from Frontiers in Microbiology
#12,532
of 25,070 outputs
Outputs of similar age
#176,998
of 316,999 outputs
Outputs of similar age from Frontiers in Microbiology
#323
of 539 outputs
Altmetric has tracked 22,992,311 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 25,070 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 316,999 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 539 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.