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Porcine Models of Biofilm Infections with Focus on Pathomorphology

Overview of attention for article published in Frontiers in Microbiology, October 2017
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Title
Porcine Models of Biofilm Infections with Focus on Pathomorphology
Published in
Frontiers in Microbiology, October 2017
DOI 10.3389/fmicb.2017.01961
Pubmed ID
Authors

Louise K. Jensen, Anne S. B. Johansen, Henrik E. Jensen

Abstract

Bacterial biofilm formation is one of the main reasons for a negative treatment outcome and a high recurrence rate for many chronic infections in humans. The optimal way to study both the biofilm forming bacteria and the host response simultaneously is by using discriminative, reliable, and reproducible animal models of the infections. In this review, the advantages of in vivo studies are compared to in vitro studies of biofilm formation in infectious diseases. The pig is the animal of choice when developing and applying large animal models of infectious diseases due to its similarity of anatomy, physiology, and immune system to humans. Furthermore, conventional pigs spontaneously develop many of the same chronic bacterial infections as seen in humans. Therefore, in this review porcine models of five different infectious diseases all associated with biofilm formation and chronicity in humans are described. The infectious diseases are: chronic wounds, endocarditis, pyelonephritis, hematogenous osteomyelitis, and implant-associated osteomyelitis (IAO).

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 66 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 66 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 27%
Student > Master 12 18%
Researcher 11 17%
Student > Bachelor 4 6%
Other 3 5%
Other 9 14%
Unknown 9 14%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 12 18%
Medicine and Dentistry 10 15%
Immunology and Microbiology 8 12%
Agricultural and Biological Sciences 8 12%
Veterinary Science and Veterinary Medicine 4 6%
Other 10 15%
Unknown 14 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 October 2017.
All research outputs
#17,918,662
of 23,006,268 outputs
Outputs from Frontiers in Microbiology
#17,397
of 25,107 outputs
Outputs of similar age
#232,083
of 324,389 outputs
Outputs of similar age from Frontiers in Microbiology
#383
of 522 outputs
Altmetric has tracked 23,006,268 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 25,107 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one is in the 22nd percentile – i.e., 22% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 324,389 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 522 others from the same source and published within six weeks on either side of this one. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.