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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Occurrence of blaNDM Variants Among Enterobacteriaceae From a Neonatal Intensive Care Unit in a Northern India Hospital
|
|---|---|
| Published in |
Frontiers in Microbiology, March 2018
|
| DOI | 10.3389/fmicb.2018.00407 |
| Pubmed ID | |
| Authors |
Nayeem Ahmad, Shamsi Khalid, Syed M. Ali, Asad U. Khan |
| Abstract |
Carbapenem-resistance among enterobacteriaceae has become a global health concern. The objective of this study was to understand NDM producing enterobacteriaceae and their genetic basis of resistance, spreading in neonatal intensive care unit. Carbapenem resistant NDM producing enterobacteriaceae isolates were recovered from rectal swab and blood sample of infants admitted in NICU. These were determined by using Carba-NP test. All isolates were identified using BD PhoenixTM-100and MICs were determined by broth microdilution method. TheblaNDMand associated resistant markers were checked by PCR followed by sequencing. Moreover, ERIC-PCR and genetic environment ofblaNDMgene were also performed for the analysis of clonal relationship and genetic surrounding of the strains. We characterized 44 isolates withblaNDMvariants inEscherichia coli(45.5%),Klebsiella pneumoniae(40.9%),Citrobacter freundii(4.5%),Citrobacter braakii(2.3%),Klebsiella oxytoca(2.3%),Enterobacter cloacae(2.3%),Enterobacter aerogenes(2.2%) from NICU, showing resistance against all antibiotics except colistin and polymixin B. ISAba125and bleomycin gene were found surrounding allblaNDMvariants, besides class I integron on plasmid. (ERIC)-PCR data revealed non-clonal relatedness among most of the isolates. The transfer of resistant markers was confirmed by conjugation experiment. The PCR-based replicon typing was carried out using DNA of transconjugants. These isolates carried NDM-1 (20.45%), NDM-4 (36.36%), NDM-5 (38.64%), NDM-7 (4.55%), along with OXA, CMY, and SHV variants on conjugative plasmid of IncFIA, IncFIC, IncF, IncK, IncFIB, IncB/O, IncHI1, IncP, IncY, IncFIIA, IncI1, and IncN types. An increased number of carbapenem-resistant NDM producing enterobacteriaceae isolates recovered from NICU which is alarming signal for health workers and policy makers. Hence, it is utmost important to think about infection control measures. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 60 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 9 | 15% |
| Student > Ph. D. Student | 7 | 12% |
| Student > Bachelor | 6 | 10% |
| Student > Postgraduate | 5 | 8% |
| Lecturer | 3 | 5% |
| Other | 8 | 13% |
| Unknown | 22 | 37% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 8 | 13% |
| Immunology and Microbiology | 8 | 13% |
| Biochemistry, Genetics and Molecular Biology | 7 | 12% |
| Agricultural and Biological Sciences | 3 | 5% |
| Veterinary Science and Veterinary Medicine | 2 | 3% |
| Other | 8 | 13% |
| Unknown | 24 | 40% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 April 2018.
All research outputs
#3,966,609
of 23,026,672 outputs
Outputs from Frontiers in Microbiology
#3,744
of 25,153 outputs
Outputs of similar age
#78,648
of 332,611 outputs
Outputs of similar age from Frontiers in Microbiology
#146
of 591 outputs
Altmetric has tracked 23,026,672 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 25,153 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 332,611 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 591 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.