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Dissemination of KPC-2-Encoding IncX6 Plasmids Among Multiple Enterobacteriaceae Species in a Single Chinese Hospital

Overview of attention for article published in Frontiers in Microbiology, March 2018
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Title
Dissemination of KPC-2-Encoding IncX6 Plasmids Among Multiple Enterobacteriaceae Species in a Single Chinese Hospital
Published in
Frontiers in Microbiology, March 2018
DOI 10.3389/fmicb.2018.00478
Pubmed ID
Authors

Bing Li, Jiao Feng, Zhe Zhan, Zhe Yin, Qiyu Jiang, Ping Wei, Xingming Chen, Bo Gao, Jun Hou, Panyong Mao, Weili Wu, Weijun Chen, Yigang Tong, Jinglin Wang, Boan Li, Dongsheng Zhou

Abstract

Forty-five KPC-producingEnterobacteriaceaestrains were isolated from multiple departments in a Chinese public hospital from 2014 to 2015. Genome sequencing of four representative strains, namelyProteus mirabilisGN2,Serratia marcescensGN26,Morganella morganiiGN28, andKlebsiella aerogenesE20, indicated the presence ofblaKPC-2-carrying IncX6 plasmids pGN2-KPC, pGN26-KPC, pGN28-KPC, and pE20-KPC in the four strains, respectively. These plasmids were genetically closely related to one another and to the only previously sequenced IncX6 plasmid, pKPC3_SZ. Each of the plasmids carried a single accessory module containing theblaKPC-2/3-carrying ΔTn6296derivatives. The ΔTn6292element from pGN26-KPC also containedqnrS, which was absent from all other plasmids. Overall, pKPC3_SZ-likeblaKPC-carrying IncX6 plasmids were detected by PCR in 44.4% of the KPC-producing isolates, which includedK. aerogenes, P. mirabilis, S. marcescens, M. morganii, Escherichia coli, andKlebsiella pneumoniae, and were obtained from six different departments of the hospital. Data presented herein provided insights into the genomic diversity and evolution of IncX6 plasmids, as well as the dissemination and epidemiology ofblaKPC-carrying IncX6 plasmids amongEnterobacteriaceaein a hospital setting.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 24 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 29%
Student > Master 4 17%
Student > Postgraduate 2 8%
Student > Doctoral Student 2 8%
Student > Ph. D. Student 1 4%
Other 0 0%
Unknown 8 33%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 3 13%
Immunology and Microbiology 3 13%
Agricultural and Biological Sciences 3 13%
Medicine and Dentistry 2 8%
Environmental Science 1 4%
Other 1 4%
Unknown 11 46%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 April 2018.
All research outputs
#18,601,965
of 23,041,514 outputs
Outputs from Frontiers in Microbiology
#19,603
of 25,180 outputs
Outputs of similar age
#258,152
of 332,306 outputs
Outputs of similar age from Frontiers in Microbiology
#486
of 604 outputs
Altmetric has tracked 23,041,514 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 25,180 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one is in the 9th percentile – i.e., 9% of its peers scored the same or lower than it.
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We're also able to compare this research output to 604 others from the same source and published within six weeks on either side of this one. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.