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A Proposal of Remedies for Oral Diseases Caused by Candida: A Mini Review

Overview of attention for article published in Frontiers in Microbiology, July 2018
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3 X users

Citations

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31 Dimensions

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92 Mendeley
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Title
A Proposal of Remedies for Oral Diseases Caused by Candida: A Mini Review
Published in
Frontiers in Microbiology, July 2018
DOI 10.3389/fmicb.2018.01522
Pubmed ID
Authors

Tomoko Ohshima, Satoshi Ikawa, Katsuhisa Kitano, Nobuko Maeda

Abstract

An opportunistic pathogen, Candida is not only related to oral problems such as oral candidiasis and denture stomatitis, but also to systemic diseases such as aspiration pneumonia and fungemia. The carriage rate of Candida species in the oral cavity of individuals wearing dentures and with removable orthodontic appliances, has increased. Moreover, it is one of the causal pathogens in refractory infected root canals because of its resistance to antifungal drugs in root canal therapy and poses a great challenge during the treatment of patients. This problem has led to the search for alternative strategies for the treatment and management of C. albicans infections. In this mini review, recent preventive strategies against Candida infection in the oral mucosa with natural product-derived antifungal molecules were discussed. Inhibitory strategies by introducing competitive naturally-derived antifungal peptide molecules with Candida adhesion molecules were specifically introduced. In addition, novel sterilization methods for Candida-infected root canals and tooth structures in the oral cavity were considered, with focused attention on the activities of reactive oxygen species. The possibility of application of these novel strategies in clinical treatments and daily life was also proposed.

X Demographics

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The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 92 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 92 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 12 13%
Student > Doctoral Student 10 11%
Student > Bachelor 7 8%
Student > Ph. D. Student 6 7%
Student > Postgraduate 5 5%
Other 19 21%
Unknown 33 36%
Readers by discipline Count As %
Medicine and Dentistry 33 36%
Immunology and Microbiology 6 7%
Unspecified 4 4%
Engineering 4 4%
Pharmacology, Toxicology and Pharmaceutical Science 2 2%
Other 8 9%
Unknown 35 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 July 2018.
All research outputs
#14,419,368
of 23,094,276 outputs
Outputs from Frontiers in Microbiology
#12,605
of 25,264 outputs
Outputs of similar age
#185,421
of 326,642 outputs
Outputs of similar age from Frontiers in Microbiology
#389
of 751 outputs
Altmetric has tracked 23,094,276 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 25,264 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 326,642 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 751 others from the same source and published within six weeks on either side of this one. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.