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Bacterial Strategies to Preserve Cell Wall Integrity Against Environmental Threats

Overview of attention for article published in Frontiers in Microbiology, August 2018
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

Mentioned by

blogs
2 blogs
twitter
13 X users

Citations

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70 Dimensions

Readers on

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155 Mendeley
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Title
Bacterial Strategies to Preserve Cell Wall Integrity Against Environmental Threats
Published in
Frontiers in Microbiology, August 2018
DOI 10.3389/fmicb.2018.02064
Pubmed ID
Authors

Akhilesh K. Yadav, Akbar Espaillat, Felipe Cava

Abstract

Bacterial cells are surrounded by an exoskeleton-like structure, the cell wall, composed primarily of the peptidoglycan (PG) sacculus. This structure is made up of glycan strands cross-linked by short peptides generating a covalent mesh that shapes bacteria and prevents their lysis due to their high internal osmotic pressure. Even though the PG is virtually universal in bacteria, there is a notable degree of diversity in its chemical structure. Modifications in both the sugars and peptides are known to be instrumental for bacteria to cope with diverse environmental challenges. In this review, we summarize and discuss the cell wall strategies to withstand biotic and abiotic environmental insults such as the effect of antibiotics targeting cell wall enzymes, predatory PG hydrolytic proteins, and PG signaling systems. Finally we will discuss the opportunities that species-specific PG variability might open to develop antimicrobial therapies.

X Demographics

X Demographics

The data shown below were collected from the profiles of 13 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 155 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 155 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 26 17%
Student > Bachelor 21 14%
Researcher 16 10%
Student > Master 12 8%
Student > Doctoral Student 9 6%
Other 14 9%
Unknown 57 37%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 36 23%
Agricultural and Biological Sciences 23 15%
Immunology and Microbiology 14 9%
Chemistry 11 7%
Medicine and Dentistry 8 5%
Other 8 5%
Unknown 55 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 20. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 May 2024.
All research outputs
#1,921,868
of 25,967,806 outputs
Outputs from Frontiers in Microbiology
#1,255
of 30,017 outputs
Outputs of similar age
#38,376
of 348,670 outputs
Outputs of similar age from Frontiers in Microbiology
#58
of 707 outputs
Altmetric has tracked 25,967,806 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 30,017 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 348,670 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 707 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.