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MicroRNAs as potential target in human bone and soft tissue sarcoma therapeutics

Overview of attention for article published in Frontiers in Molecular Biosciences, June 2015
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3 X users

Citations

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38 Dimensions

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28 Mendeley
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Title
MicroRNAs as potential target in human bone and soft tissue sarcoma therapeutics
Published in
Frontiers in Molecular Biosciences, June 2015
DOI 10.3389/fmolb.2015.00031
Pubmed ID
Authors

Jyotika Varshney, Subbaya Subramanian

Abstract

Sarcomas are highly aggressive heterogeneous tumors that are mesenchymal in origin. There have been vast advancements on identifying diagnostic markers for sarcomas including chromosomal translocations, but very little progress has been made to identify targeted therapies against them. The tumor heterogeneity, genetic complexity and the lack of drug studies make it challenging to recognize the potential targets and also accounts for the inadequate treatments in sarcomas. In recent years, microRNAs that are a part of small non-coding RNAs have shown promising results as potential diagnostic and prognostic biomarkers in multiple sarcoma types. This review focuses on the current knowledge of the microRNAs that are deregulated in sarcomas, and an insight on the strategies to target these microRNAs that are essential for developing improved therapies for various human sarcomas.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 28 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 21%
Student > Bachelor 5 18%
Student > Master 4 14%
Student > Ph. D. Student 3 11%
Professor 2 7%
Other 4 14%
Unknown 4 14%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 8 29%
Medicine and Dentistry 6 21%
Agricultural and Biological Sciences 4 14%
Pharmacology, Toxicology and Pharmaceutical Science 1 4%
Veterinary Science and Veterinary Medicine 1 4%
Other 0 0%
Unknown 8 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 July 2015.
All research outputs
#15,333,633
of 22,807,037 outputs
Outputs from Frontiers in Molecular Biosciences
#1,544
of 3,770 outputs
Outputs of similar age
#154,334
of 264,367 outputs
Outputs of similar age from Frontiers in Molecular Biosciences
#12
of 26 outputs
Altmetric has tracked 22,807,037 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,770 research outputs from this source. They receive a mean Attention Score of 3.3. This one has gotten more attention than average, scoring higher than 55% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 264,367 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 26 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.