Title |
Potential Roles of Adropin in Central Nervous System: Review of Current Literature
|
---|---|
Published in |
Frontiers in Molecular Biosciences, June 2016
|
DOI | 10.3389/fmolb.2016.00025 |
Pubmed ID | |
Authors |
Shima Shahjouei, Saeed Ansari, Tayebeh Pourmotabbed, Ramin Zand |
Abstract |
Adropin is a 4.9 kDa peptide that is important for maintenance of metabolic and non-metabolic homeostasis. It regulates glucose and fatty acid metabolism and is involved in endothelial cell function and endothelial nitric oxide (NO) synthase bioactivity as well as physical activity and motor coordination. Adropin is expressed in many tissues and organs including central nervous system (CNS). This peptide plays a crucial role in the development of various CNS disorders such as stroke, schizophrenia, bipolar disorder as well as Alzheimer's, Parkinson's, and Huntington's diseases. In this comprehensive review, the potential roles of adropin in cellular signaling pathways that lead to pathogenesis and/or treatment of CNS disorders will be discussed. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Switzerland | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 62 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 8 | 13% |
Student > Doctoral Student | 7 | 11% |
Student > Master | 6 | 10% |
Researcher | 5 | 8% |
Student > Postgraduate | 5 | 8% |
Other | 8 | 13% |
Unknown | 23 | 37% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 13 | 21% |
Neuroscience | 5 | 8% |
Biochemistry, Genetics and Molecular Biology | 4 | 6% |
Sports and Recreations | 4 | 6% |
Psychology | 2 | 3% |
Other | 8 | 13% |
Unknown | 26 | 42% |