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Mendeley readers
Attention Score in Context
| Title |
Genome-Wide Transcriptional Regulation and Chromosome Structural Arrangement by GalR in E. coli
|
|---|---|
| Published in |
Frontiers in Molecular Biosciences, November 2016
|
| DOI | 10.3389/fmolb.2016.00074 |
| Pubmed ID | |
| Authors |
Zhong Qian, Andrei Trostel, Dale E. A. Lewis, Sang Jun Lee, Ximiao He, Anne M. Stringer, Joseph T. Wade, Thomas D. Schneider, Tim Durfee, Sankar Adhya |
| Abstract |
The regulatory protein, GalR, is known for controlling transcription of genes related to D-galactose metabolism in Escherichia coli. Here, using a combination of experimental and bioinformatic approaches, we identify novel GalR binding sites upstream of several genes whose function is not directly related to D-galactose metabolism. Moreover, we do not observe regulation of these genes by GalR under standard growth conditions. Thus, our data indicate a broader regulatory role for GalR, and suggest that regulation by GalR is modulated by other factors. Surprisingly, we detect regulation of 158 transcripts by GalR, with few regulated genes being associated with a nearby GalR binding site. Based on our earlier observation of long-range interactions between distally bound GalR dimers, we propose that GalR indirectly regulates the transcription of many genes by inducing large-scale restructuring of the chromosome. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 16 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 4 | 25% |
| Student > Ph. D. Student | 3 | 19% |
| Unspecified | 2 | 13% |
| Professor | 1 | 6% |
| Student > Master | 1 | 6% |
| Other | 1 | 6% |
| Unknown | 4 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 8 | 50% |
| Unspecified | 2 | 13% |
| Chemistry | 1 | 6% |
| Engineering | 1 | 6% |
| Unknown | 4 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 November 2016.
All research outputs
#18,482,034
of 22,901,818 outputs
Outputs from Frontiers in Molecular Biosciences
#1,964
of 3,819 outputs
Outputs of similar age
#203,906
of 270,398 outputs
Outputs of similar age from Frontiers in Molecular Biosciences
#12
of 20 outputs
Altmetric has tracked 22,901,818 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,819 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 33rd percentile – i.e., 33% of its peers scored the same or lower than it.
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We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.