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Challenges and opportunities for characterizing cognitive aging across species

Overview of attention for article published in Frontiers in Aging Neuroscience, January 2012
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Title
Challenges and opportunities for characterizing cognitive aging across species
Published in
Frontiers in Aging Neuroscience, January 2012
DOI 10.3389/fnagi.2012.00006
Pubmed ID
Authors

Erik D. Roberson, R. Anthony DeFazio, Carol A. Barnes, Gene E. Alexander, Jennifer L. Bizon, Dawn Bowers, Thomas C. Foster, Elizabeth L. Glisky, Bonnie E. Levin, Lee Ryan, Clinton B. Wright, David S. Geldmacher

Abstract

The gradual decline of cognitive ability with age, even in the absence of overt brain disease, is a growing problem. Although cognitive aging is a common and feared accompaniment of the aging process, its underlying mechanisms are not well understood and there are no highly effective means to prevent it. Additional research on cognitive aging is sorely needed, and methods that enable ready translation between human subjects and animal models stand to provide the most benefit. Here and in the six companion pieces in this special issue, we discuss a variety of challenges and opportunities for studying cognitive aging across species. We identify tests of associative memory, recognition memory, spatial and contextual memory, and working memory and executive function as cognitive domains that are age-sensitive and amenable to testing with parallel means in both humans and animal models. We summarize some of the important challenges in using animal models to test cognition. We describe unique opportunities to study cognitive aging in human subjects, such as those provided by recent large-scale initiatives to characterize cognition in large groups of subjects across the lifespan. Finally, we highlight some of the challenges of studying cognitive aging in human subjects.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 62 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 2%
Puerto Rico 1 2%
Canada 1 2%
Brazil 1 2%
Unknown 58 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 19%
Student > Ph. D. Student 11 18%
Student > Master 7 11%
Student > Doctoral Student 6 10%
Professor 5 8%
Other 13 21%
Unknown 8 13%
Readers by discipline Count As %
Psychology 14 23%
Neuroscience 13 21%
Medicine and Dentistry 8 13%
Agricultural and Biological Sciences 7 11%
Biochemistry, Genetics and Molecular Biology 2 3%
Other 3 5%
Unknown 15 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 September 2012.
All research outputs
#20,166,700
of 22,678,224 outputs
Outputs from Frontiers in Aging Neuroscience
#4,252
of 4,721 outputs
Outputs of similar age
#221,187
of 244,101 outputs
Outputs of similar age from Frontiers in Aging Neuroscience
#17
of 22 outputs
Altmetric has tracked 22,678,224 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,721 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 244,101 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.